Summary 415 million people live with diabetes worldwide, and an estimated 193 million
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …

Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …

In order to ensure normal body function, the human body is dependent on a tight control of
its blood glucose levels. This is accomplished by a highly sophisticated network of various …

Type 2 diabetes mellitus (DM) is a chronic metabolic disorder in which prevalence has been
increasing steadily all over the world. As a result of this trend, it is fast becoming an epidemic …

Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl
cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular …

Type 2 diabetes mellitus is the most prevalent metabolic disorder characterized by
hyperglycemia, hyperlipidemia as well as insulin resistance and is affecting the lives of a …

Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …

Prenylated flavonoids, a unique class of flavonoids which combine a flavonoid skeleton and
a lipophilic prenyl side-chain, possess great potential biological activities including …

Target-based drug discovery is the dominant paradigm of drug discovery; however, a
comprehensive evaluation of its real-world efficiency is lacking. Here, a manual systematic …

Type 2 diabetes mellitus is a chronic metabolic disorder that results from defects in both
insulin secretion and insulin action. An elevated rate of basal hepatic glucose production in …