The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

In the central nervous system (CNS), astrocytes form networks interconnected by gap
junctions made from connexins of the subtypes Cx30 and Cx43. When unopposed by an …

Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy, yet
approximately one-third of patients are refractory to current anticonvulsive drugs, which …

Depression is a chronic, recurring, and serious mood disorder that afflicts up to 20% of the
global population. The monoamine hypothesis has dominated our understanding of the …

The contribution of reactive gliosis to the pathological phenotype of Alzheimer's disease
(AD) opened the way for therapeutic strategies targeting glial cells instead of neurons. In …

Diverse studies have suggested that cytoplasmic inclusions of misfolded α‐synuclein in
neuronal and glial cells are main pathological features of different α‐synucleinopathies …

Acute brain injuries (ABIs) encompass a broad spectrum of primary injuries such as
ischemia, hypoxia, trauma, and hemorrhage that converge into secondary injury where …

Accumulating evidence shows a key function for astrocytic connexin43 (Cx43) signaling in
epilepsy. However, the lack of experimental distinction between Cx43 gap junction channels …

Clinical evidence has revealed that children born from mothers exposed to viral and
bacterial pathogens during pregnancy are more likely to suffer various neurological …

A mounting body of evidence indicates that adolescents are specially more susceptible to
alcohol influence than adults. However, the mechanisms underlying this phenomenon …