The molecular modelling approach was applied to a series of nineteen curcumin analogues
to find the possible PfRIO2 kinase inhibitory action. A putative active site in flexible loop (S1) …

In Africa, malaria kills one child each minute. It is also responsible for about one million
deaths worldwide each year. Plasmodium falciparum, is the protozoan responsible for the …

The pharmacophoric hybridization and computational design approach were applied to
generate a novel series of α-pyrone analogs as plausible anti-malarial lead candidate. A …

Curcumin is well known to possess diverse therapeutic properties, one of which is its
antimalarial activity. It has been reported to show synergistic activity in combination with …

Malaria is a parasitic disease, widespread along the tropical regions of the world. The
disease has killed 4, 38,000 individuals in the year 2015 (WHO). The malaria parasite …