Succinate dehydrogenase (SDH) also known as complex II or succinate: quinone
oxidoreductase is an enzyme involved in both oxidative phosphorylation and tricarboxylic …

Since their discovery, heat shock proteins (HSPs) have been identified in all domains of life,
which demonstrates their importance and conserved functional role in maintaining protein …

Molecular chaperones are a family of proteins that maintain cellular protein homeostasis
through non-covalent peptide folding and quality control mechanisms. The chaperone …

Hsp70s (heat shock protein 70s) are a class of molecular chaperones that are highly
conserved and ubiquitous in organisms ranging from microorganisms to plants and humans …

We and others have reported mutations in LONP1, a gene coding for a mitochondrial
chaperone and protease, as the cause of the human CODAS (cerebral, ocular, dental …

Mortalin is a chaperone protein that regulates physiological functions of cells. Its
multifactorial role allows cells to survive pathological conditions. Pharmacological, chemical …

Heat shock proteins (HSP) are critical elements for the preservation of cellular homeostasis
by participating in an array of biological processes. In addition, HSP play an important role in …

Heat shock proteins (HSPs) are ubiquitous polypeptides expressed in all living organisms
that participate in several basic cellular processes, including protein folding, from which their …

Overexpression of oncoproteins is a major cause of treatment failure using current
chemotherapeutic drugs. Drug‐induced degradation of oncoproteins is feasible and can …

Mitochondria play an essential role in maintaining energy homeostasis and cellular survival.
In the brain, higher ATP production is required by mature neurons for communication. Most …