[HTML][HTML] Male sexual dysfunction: A review of literature on its pathological mechanisms, potential risk factors, and herbal drug intervention

L Chen, G Shi, D Huang, Y Li, C Ma, M Shi, B Su… - Biomedicine & …, 2019 - Elsevier
Sexual dysfunction (SD) is a disorder of sexual behavior and sexual sensation that appears
as an abnormality or absence of sexual psychology and physiological reaction. It is a …

Efficacy of α-lipoic acid in diabetic neuropathy

N Papanas, D Ziegler - Expert Opinion on Pharmacotherapy, 2014 - Taylor & Francis
Introduction: Neuropathy is a serious complication of diabetes. Its management focuses on
glycaemic control, multifactorial cardiovascular risk intervention, pathogenesis-oriented …

[PDF][PDF] Modifying risk factors in the management of erectile dysfunction: a review

KJ DeLay, N Haney… - The world journal of …, 2016 - synapse.koreamed.org
Erectile dysfunction (ED) is prevalent among men and its presence is often an indicator of
systemic disease. Risk factors for ED include cardiovascular disease, hypertension …

Physiological effect and therapeutic application of alpha lipoic acid

S Park, U Karunakaran, N Ho Jeoung… - Current medicinal …, 2014 - ingentaconnect.com
Reactive oxygen species and reactive nitrogen species promote endothelial dysfunction in
old ageand contribute to the development of cardiovascular diseases such as …

Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis

K Tajima, K Ikeda, HY Chang, CH Chang… - Nature …, 2019 - nature.com
Thermogenesis in brown adipose tissue (BAT) declines with age; however, what regulates
this process is poorly understood. Here, we identify mitochondrial lipoylation as a previously …

Benefits and health implications of testosterone therapy in men with testosterone deficiency

AM Traish - Sexual medicine reviews, 2018 - academic.oup.com
Abstract Introduction Testosterone (T) deficiency (TD; hypogonadism) has deleterious effects
on men's health; negatively affects glycometabolic and cardiometabolic functions, body …

Optimized vinpocetine-loaded vitamin E D-α-tocopherol polyethylene glycol 1000 succinate-alpha lipoic acid micelles as a potential transdermal drug delivery system …

OAA Ahmed, KM El-Say, BM Aljaeid… - International Journal …, 2019 - Taylor & Francis
Background Vinpocetine (VNP), a semisynthetic natural product, is used as a vasodilator for
cerebrovascular and age-related memory disorders. VNP suffers from low oral bioavailability …

Adverse health effects of testosterone deficiency (TD) in men

AM Traish - Steroids, 2014 - Elsevier
Testosterone and its metabolite, 5α-dihydrotestosterone are critical metabolic and vascular
hormones, which regulate a host of biochemical pathways including carbohydrate, lipid and …

Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin–Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis …

H Lin, T Wang, Y Ruan, K Liu, H Li… - The Journal of …, 2018 - academic.oup.com
Introduction Erectile dysfunction (ED), which is common in patients with diabetes mellitus
(DM), seriously affects quality of life. Previous studies on the treatment of DM–induced ED …

Efficacy and safety of oral alpha-lipoic acid supplementation for type 2 diabetes management: A systematic review and dose–response meta-analysis of randomized …

AT Jibril, A Jayedi, S Shab-Bidar - Endocrine Connections, 2022 - ec.bioscientifica.com
Objective To examine the dose-dependent influence of oral alpha-lipoic acid (ALA)
supplementation on cardiometabolic risk factors in patients with type 2 diabetes (T2D) …