T-cell acute lymphoblastic leukemia (T-ALL), a form of T-cell malignancy, is a typically
aggressive hematological malignancy with high rates of disease relapse and a poor …

Simple Summary Glioblastoma is the most prevalent cerebral cancer in adults without
proven therapy. Chimeric antigen receptor T cell treatment has demonstrated good clinical …

Cellular immunotherapy represented by CD19-directed chimeric antigen receptor T (CAR-T)
cells has achieved great success in recent years. An increasing number of CAR-T therapies …

Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of rare hematologic
malignancies accounting for less than 10% of non-Hodgkin lymphomas. The 2016 …

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer that
frequently occurs in children and adolescents, which results from the transformation of …

Chimeric antigen receptor T cell (CAR-T) therapy has proven successful for B cell
lymphomas and leukaemias. This success has inspired the development of CAR-T for T cell …

Objective. To explore the immune cell therapy for T cell lymphoma, we developed CD4‐
specific chimeric antigen receptor‐(CAR‐) engineered T cells (CD4CART), and the cytotoxic …

Chimeric antigen receptor T cells (CAR-Ts) targeted against CD19 have shown impressive
activity in patients with B-cell leukemias and lymphomas. This has revolutionized the …

Purpose Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is rare in China and
case reports are varied. We conducted an in-depth analysis of newly diagnosed children …

Despite medical advances in recent decades with improvement in survival rates (Lenk et al.,
Cancer Metastasis Rev. 2020; 39: 173–87; Meyer and Hermiston. Cancer Drug Resist …