Acute stress puts cells at risk, and rapid adaptation is crucial for maximizing cell survival.
Cellular adaptation mechanisms include modification of certain aspects of cell physiology …

An appropriate response and adaptation to hyperosmolarity, ie., an external osmolarity that
is higher than the physiological range, can be a matter of life or death for all cells. It is …

Protein modifications provide cells with exquisite temporal and spatial control of protein
function. Ubiquitin is among the most important modifiers, serving both to target hundreds of …

Cells coordinate intracellular activities in response to changes in the extracellular
environment to maximize their probability of survival and proliferation. Eukaryotic cells need …

Living cells exposed to stressful environmental situations can elicit cellular responses that
guarantee maximal cell survival. Most of these responses are mediated by mitogen …

Genomic analysis has revealed the existence of a large number of long noncoding RNAs
(lncRNAs) with different functions in a variety of organisms, including yeast. Cells display …

Protein ubiquitination is a key post-translational modification that regulates diverse cellular
processes in eukaryotic cells. The specificity of ubiquitin (Ub) signalling for different …

Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden
changes in the environment. Several aspects of cell physiology change during adaptation …

The unconventional prefoldin URI/RMP, in humans, and its orthologue in yeast, Bud27, have
been proposed to participate in the biogenesis of the RNA polymerases. However, this role …

Alzheimer's Disease (AD) is a progressive multifactorial age-related neurodegenerative
disorder that causes the majority of deaths due to dementia in the elderly. Although various …