2019 Global NAFLD prevalence: a systematic review and meta-analysis

MH Le, YH Yeo, X Li, J Li, B Zou, Y Wu, Q Ye… - Clinical …, 2022 - Elsevier
Background & Aims The increasing rates of obesity and type 2 diabetes mellitus may lead to
increased prevalence of nonalcoholic fatty liver disease (NAFLD). We aimed to determine …

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

DQ Huang, HB El-Serag, R Loomba - Nature reviews Gastroenterology …, 2021 - nature.com
One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …

Current therapies and new developments in NASH

JF Dufour, QM Anstee, E Bugianesi, S Harrison… - Gut, 2022 - gut.bmj.com
Non-alcoholic steatohepatitis is becoming the most important aetiology for advanced liver
disease. There has been important progress in the field in recent years and the complexity of …

From NASH to HCC: current concepts and future challenges

QM Anstee, HL Reeves, E Kotsiliti, O Govaere… - Nature reviews …, 2019 - nature.com
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …

Complications, morbidity and mortality of nonalcoholic fatty liver disease

A Mantovani, E Scorletti, A Mosca, A Alisi, CD Byrne… - Metabolism, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized public health
problem, affecting up to a quarter of the world's adult population. The burden of NAFLD is …

MAFLD: A multisystem disease

RM Pipitone, C Ciccioli, G Infantino… - Therapeutic …, 2023 - journals.sagepub.com
Nonalcoholic fatty liver disease (NAFLD), affecting about 25% of general population and
more than 50% of dysmetabolic patients, is an emerging cause of chronic liver disease and …

Non-alcoholic fatty liver disease and increased risk of incident extrahepatic cancers: a meta-analysis of observational cohort studies

A Mantovani, G Petracca, G Beatrice, A Csermely… - Gut, 2022 - gut.bmj.com
Objective We performed a meta-analysis of observational studies to quantify the magnitude
of the association between non-alcoholic fatty liver disease (NAFLD) and risk of extrahepatic …

Nonalcoholic steatohepatitis is the fastest growing cause of hepatocellular carcinoma in liver transplant candidates

Z Younossi, M Stepanova, JP Ong, IM Jacobson… - Clinical …, 2019 - Elsevier
Background & Aims Although hepatitis B and C have been the main drivers of hepatocellular
carcinoma (HCC), nonalcoholic steatohepatitis (NASH) has recently become an important …

Metabolic-associated fatty liver disease (MAFLD): a multi-systemic disease beyond the liver

E Kaya, Y Yilmaz - Journal of clinical and translational …, 2021 - pmc.ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a multisystemic clinical condition that presents
with a wide spectrum of extrahepatic manifestations, such as obesity, type 2 diabetes …

[HTML][HTML] Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

LA Orci, M Sanduzzi-Zamparelli, B Caballol… - Clinical …, 2022 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) may be a risk factor for
hepatocellular carcinoma (HCC), but the extent of this association still needs to be …