Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Dendritic mesoporous nanoparticles: structure, synthesis and properties

C Xu, C Lei, Y Wang, C Yu - Angewandte Chemie International …, 2022 - Wiley Online Library
Recently, dendritic mesoporous silica nanoparticles with widespread applications have
attracted great interest. Despite many publications (> 800), the terminology “dendritic” is …

Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy

Y Zheng, Y Han, Q Sun, Z Li - Exploration, 2022 - Wiley Online Library
Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Acid‐ionizable iron nanoadjuvant augments STING activation for personalized vaccination immunotherapy of cancer

F Chen, T Li, H Zhang, M Saeed, X Liu… - Advanced …, 2023 - Wiley Online Library
The critical challenge for cancer vaccine‐induced T‐cell immunity is the sustained activation
of antigen cross‐presentation in antigen‐presenting cells (APCs) with innate immune …

Silica-based nanoparticles for biomedical applications: from nanocarriers to biomodulators

Y Yang, M Zhang, H Song, C Yu - Accounts of chemical research, 2020 - ACS Publications
Conspectus Silica-based nanoparticles (SNPs) are a classic type of material employed in
biomedical applications because of their excellent biocompatibility and tailorable …

Hybrid‐membrane‐decorated prussian blue for effective cancer immunotherapy via tumor‐associated macrophages polarization and hypoxia relief

L Hou, X Gong, J Yang, H Zhang, W Yang… - Advanced …, 2022 - Wiley Online Library
Both tumor‐associated macrophages (TAMs) and hypoxia condition severely restrict the
antitumor potency during cancer immunotherapy. It is essential to overcome the two issues …

Superparamagnetic iron oxide nanoparticles (SPION): from fundamentals to state-of-the-art innovative applications for cancer therapy

T Vangijzegem, V Lecomte, I Ternad, L Van Leuven… - Pharmaceutics, 2023 - mdpi.com
Despite significant advances in cancer therapy over the years, its complex pathological
process still represents a major health challenge when seeking effective treatment and …

The role of iron regulation in immunometabolism and immune-related disease

SJF Cronin, CJ Woolf, G Weiss… - Frontiers in molecular …, 2019 - frontiersin.org
Immunometabolism explores how the intracellular metabolic pathways in immune cells can
regulate their function under different micro-environmental and (patho-)-physiological …

A tumor‐microenvironment‐responsive nanocomposite for hydrogen sulfide gas and trimodal‐enhanced enzyme dynamic therapy

B Liu, S Liang, Z Wang, Q Sun, F He, S Gai… - Advanced …, 2021 - Wiley Online Library
Recently, enzyme dynamic therapy (EDT) has drawn much attention as a new type of
dynamic therapy. However, the selection of suitable nanocarriers to deliver …

A Semiconducting Iron‐Chelating Nano‐immunomodulator for Specific and Sensitized Sono‐metallo‐immunotherapy of Cancer

S He, J Yu, M Xu, C Zhang, C Xu… - Angewandte …, 2023 - Wiley Online Library
Sono‐immunotherapy holds great potential for deep tumor inhibition; however, smart sono‐
therapeutic agents to simultaneously eliminate 'domestic'tumor cells and regulate the …