Decoding the role of CYP450 enzymes in metabolism and disease: A comprehensive review

BH Abdelmonem, NM Abdelaal, EKE Anwer… - …, 2024 - pmc.ncbi.nlm.nih.gov
Cytochrome P450 (CYP450) is a group of enzymes that play an essential role in Phase I
metabolism, with 57 functional genes classified into 18 families in the human genome, of …

Probiotics and polycystic ovary syndrome: a perspective for management in adolescents with obesity

V Calcaterra, V Rossi, G Massini, F Casini, G Zuccotti… - Nutrients, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) affects a considerable percentage of females of
reproductive age. PCOS is an obesity-related condition and its effects are greatly amplified …

Immunological and metabolic causes of infertility in polycystic ovary syndrome

AM Kicińska, RB Maksym, MA Zabielska-Kaczorowska… - Biomedicines, 2023 - mdpi.com
Infertility has been recognized as a civilizational disease. One of the most common causes
of infertility is polycystic ovary syndrome (PCOS). Closely interrelated immunometabolic …

PCOS in Adolescents—Ongoing riddles in diagnosis and treatment

B Meczekalski, O Niwczyk, A Kostrzak… - Journal of Clinical …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
women of reproductive age. A diagnosis of PCOS is established when a patient exhibits two …

[HTML][HTML] Polycystic ovarian syndrome: prevalence, predisposing factors, and awareness among adolescent and young girls of South India

A Jabeen, V Yamini, AR Amberina, MD Eshwar… - Cureus, 2022 - ncbi.nlm.nih.gov
Methods This was a prospective study that included 250 adolescent and young girls aged
between 13 and 25 years. Demographic details including age, educational status, and …

Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues

M Mathew, S Sivaprakasam, JL Phy… - Bioscience …, 2023 - portlandpress.com
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder in women with
components of significant genetic predisposition and possibly multiple, but not yet clearly …

Mechanism of LncRNA Gm2044 in germ cell development

Q Zhu, J Sun, C An, X Li, S Xu, Y He… - Frontiers in Cell and …, 2024 - frontiersin.org
Germ cell development in mammals is a complex physiological process that involves the
proliferation of primordial germ cells, meiosis, and the formation of male and female …

Updates in diagnosing polycystic ovary syndrome-related infertility

H Haddad-Filho, JAG Tosatti, FM Vale… - Expert Review of …, 2023 - Taylor & Francis
Introduction Polycystic ovary syndrome (PCOS) is a condition that affects approximately 13%
of reproductive age women and is characterized by androgen excess, menstrual irregularity …

A high-throughput RNA sequency of peripheral blood mononuclear cells reveals on inflammatory state in women with PCOS

R Heidarzadehpilehrood, M Pirhoushiaran… - Archives of Medical …, 2025 - Elsevier
Background Polycystic ovary syndrome (PCOS) is an endocrine and reproductive condition
affecting women of reproductive age, although its expression profiles and molecular …

A comprehensive genomic analysis of Chinese indigenous ningxiang pigs: genomic breed compositions, runs of homozygosity, and beyond

S Yin, Z Li, F Yang, H Guo, Q Zhao, Y Zhang… - International Journal of …, 2023 - mdpi.com
Ningxiang pigs are a renowned indigenous pig breed in China, known for their meat quality,
disease resistance, and environmental adaptability. In recent decades, consumer demand …