New developments in the production of theranostic pairs of radionuclides

SM Qaim, B Scholten, B Neumaier - Journal of Radioanalytical and …, 2018 - Springer
A brief historical background of the development of the theranostic approach in nuclear
medicine is given and seven theranostic pairs of radionuclides, namely 44g Sc/47 Sc, 64 …

Meitner-Auger Electron Emitters for Targeted Radionuclide Therapy: Mercury-197m/g and Antimony-119.

P Randhawa, AP Olson, S Chen… - Current …, 2021 - benthamdirect.com
Targeted Radionuclide Therapies (TRTs) based on Auger emitting radionuclides have the
potential to deliver extremely selective therapeutic payloads on the cellular level. However …

Clinical PET of neuroendocrine tumors using 64Cu-DOTATATE: first-in-humans study

A Pfeifer, U Knigge, J Mortensen, P Oturai… - Journal of Nuclear …, 2012 - Soc Nuclear Med
The use of positron emitter–labeled compounds for somatostatin receptor imaging (SRI) has
become attractive because of the prospect of improved spatial resolution, accelerated …

Experimental and numerical characterization of pure copper heat sinks produced by laser powder bed fusion

G Sciacca, M Sinico, G Cogo, D Bigolaro, A Pepato… - Materials & Design, 2022 - Elsevier
One of the technological challenges aimed at improving the cyclotron-based
radionuclides'(RNs) supply for Nuclear Medicine (NM), is the availability of proper heat sink …

Module-assisted preparation of 64Cu with high specific activity

S Thieme, M Walther, HJ Pietzsch, J Henniger… - Applied radiation and …, 2012 - Elsevier
In this work the production of 64Cu via the 64Ni (p, n) 64Cu reaction with optimized
conditions for low current irradiation is presented. Different target setups and cleaning steps …

[图书][B] Medical radionuclide production: science and technology

SM Qaim - 2019 - books.google.com
The work describes the production technology of standard medical radionuclides using
reactors and cyclotrons for patient diagnosis and therapy. A special focus lies on the science …

Establishing reliable Cu-64 production process: from target plating to molecular specific tumor micro-PET imaging

Q Xie, H Zhu, F Wang, X Meng, Q Ren, C Xia, Z Yang - Molecules, 2017 - mdpi.com
Copper-64 is a useful radioisotope for positron emission tomography (PET). Due to the wide
range of applications, the demand of 64Cu with low metallic impurities is increasing. Here …

[HTML][HTML] Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E [c (RGDyK)] 2 and 64Cu-NODAGA-E [c (RGDyK)] 2; in vivo imaging studies in human …

J Oxboel, M Brandt-Larsen, C Schjoeth-Eskesen… - Nuclear medicine and …, 2014 - Elsevier
Introduction The aim of this study was to synthesize and perform a side-by-side comparison
of two new tumor-angiogenesis PET tracers 68 Ga-NODAGA-E [c (RGDyK)] 2 and 64 Cu …

Efficient preparation of high-quality 64Cu for routine use

T Ohya, K Nagatsu, H Suzuki, M Fukada… - Nuclear Medicine and …, 2016 - Elsevier
Introduction Copper-64 is an attractive radionuclide for positron emission tomography and is
emerging as a radiotherapeutic agent. The demand of 64 Cu with low metallic impurities has …

Chemistry of Antimony in Radiopharmaceutical Development: Unlocking the Theranostic Potential of Sb Isotopes

A Grundmane, V Radchenko, CF Ramogida - ChemPlusChem, 2024 - Wiley Online Library
Abstract Antimony‐119 (119Sb) holds promise for radiopharmaceutical therapy (RPT),
emitting short‐range Auger and conversion electrons that can deliver cytotoxic radiation on …