This paper presents an overview of the anatomy, physiology, and biology of the lymphatic
system specifically relevant to lymphatic drug delivery. We will briefly review the classic fluid …

Lymphedema—edema that results from chronic lymphatic insufficiency—is a chronic
debilitating disease that is frequently misdiagnosed, treated too late, or not treated at all …

Background: Sentinel node (SN) biopsy appears to offer an alternative to routine axillary
lymph node dissection (ALND) for staging patients with breast cancer. Various techniques …

The concept of sentinel lymph node biopsy in breast cancer surgery relates to the fact that
the tumor drains in a logical way through the lymphatic system, from the first to upper levels …

Pupil studies in blind patients may give new insights into the function of the pupillary system.
Testing for sleepiness by means of pupillography might be used more frequently. Testing for …

The purpose of this study was to develop multimodality SPECT/MRI contrast agents for
sentinel lymph node (SLN) mapping in vivo. Methods: Nanoparticles with a solid iron oxide …

An essential prerequisite for a successful sentinel lymph node biopsy (SLNB) procedure is
an accurate map of the pattern of lymphatic drainage from the primary tumor site in each …

The lymphatic uptake of colloids, whether lipid or non-lipid in nature, is determined by the
physiology of the lymphatic system, and the physicochemical characteristics of the colloid in …

To quantitate visual findings in lymphoscintigraphy with 99m Tc-labeled stannous sulfur
colloids, a numeric index of transport kinetics was designed by combining visual …

There is a resurgence of interest in lymphoscintigraphy because of attention to the sentinel
node concept and the availability of the surgical gamma probe that can be used in the …