The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Bioactivity assessment and toxicity of crocin: a comprehensive review

SH Alavizadeh, H Hosseinzadeh - Food and chemical toxicology, 2014 - Elsevier
Since ancient times, saffron, the dried stigma of the plant Crocus sativus L. has been
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …

Functional foods against metabolic syndrome (obesity, diabetes, hypertension and dyslipidemia) and cardiovasular disease

S Mohamed - Trends in Food Science & Technology, 2014 - Elsevier
Highlights•The article reviews the current knowledge of functional foods to fight CVD•The
foods that help manage obesity or dyslipidemia and modes of action.•The various foods that …

Saffron: a natural product with potential pharmaceutical applications

E Christodoulou, NPE Kadoglou… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives Recently, a great deal of interest has been developed to isolate and investigate
novel bioactive components from natural resources with health beneficial effects. Saffron is …

Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review

A Roohbakhsh, G Karimi, M Iranshahi - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Carotenoids are a large class of natural antioxidants that occur in many vegetables, foods
and other natural sources. To date, a large number of biological properties have been …

[HTML][HTML] Safranal: from an aromatic natural product to a rewarding pharmacological agent

R Rezaee, H Hosseinzadeh - Iranian journal of basic medical …, 2013 - ncbi.nlm.nih.gov
Safranal, the main component of Crocus sativus essential oil, is thought to be the main
cause of saffron unique odor. It is now about eighty years that this compound has been …

Evaluation of the anti-diabetic activity of some common herbs and spices: providing new insights with inverse virtual screening

ASP Pereira, AJ Banegas-Luna, J Peña-García… - Molecules, 2019 - mdpi.com
Culinary herbs and spices are widely used as a traditional medicine in the treatment of
diabetes and its complications, and there are several scientific studies in the literature …

Saffron: a promising natural medicine in the treatment of metabolic syndrome

BM Razavi, H Hosseinzadeh - Journal of the Science of Food …, 2017 - Wiley Online Library
Metabolic syndrome is a disorder which encompasses obesity, high blood glucose, high
cholesterol levels and high blood pressure. Moreover, metabolic syndrome is considered as …

Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: A brief overview

S Leone, L Recinella, A Chiavaroli… - Phytotherapy …, 2018 - Wiley Online Library
Crocus sativus L.(Saffron) has long been known for multiple target therapeutic uses. The
plant metabolism is well investigated and the main metabolites related to saffron …

Saffron: a natural potent antioxidant as a promising anti-obesity drug

M Mashmoul, A Azlan, H Khaza'ai, BN Mohd Yusof… - Antioxidants, 2013 - mdpi.com
Obesity is associated with various diseases, particularly diabetes, hypertension,
osteoarthritis and heart disease. Research on possibilities of herbal extracts and isolated …