Multi-steps microfiltration of micelles from fermentation of Streptomyces tsukubaensis and its impact on proteins retention and tacrolimus yield

AS Bertan, MA Cremasco - Food and Bioproducts Processing, 2024 - Elsevier
This study reports the application of microfiltration Streptomyces tsukubaensis micelles from
fermentation broths, for tacrolimus recovery, investigating the use of a new multi-step …

Purification of rapamycin derivatives using temperature induced phase separation

MW Kayo, RS Fornicola, I Kovacik, L Kondaveti… - US Patent …, 2017 - Google Patents
US9598439B2 - Purification of rapamycin derivatives using temperature induced phase
separation - Google Patents US9598439B2 - Purification of rapamycin derivatives using …

Purification of rapamycin derivatives using temperature induced phase separation

MW Kayo, RS Fornicola, I Kovacik, L Kondaveti… - US Patent …, 2019 - Google Patents
US10202402B2 - Purification of rapamycin derivatives using temperature induced phase
separation - Google Patents US10202402B2 - Purification of rapamycin derivatives using …

Purification of rapamycin derivatives using temperature induced phase separation

MW Kayo, RS Fornicola, I Kovacik, L Kondaveti… - US Patent …, 2020 - Google Patents
US10597406B2 - Purification of rapamycin derivatives using temperature induced phase
separation - Google Patents US10597406B2 - Purification of rapamycin derivatives using …

Purification of rapamycin derivatives using temperature induced phase separation

MW Kayo, RS Fornicola, I Kovacik, L Kondaveti… - US Patent …, 2021 - Google Patents
10,202,402 B2 10,597,406 B2 2004/0266703 A1 2006/0198867 A1 2006/0222627 A1
2007/0128731 A1 2008/0146796 Al 2008/0287675 Al 2010/0029933 A1 2010/0055145 A1 …

Process for the purification of tacrolimus

W Cabri, P Paissoni, J Roletto… - US Patent App. 11/718,415, 2008 - Google Patents
(57) ABSTRACT A process for the puri? cation and recovery of Tacrolimus (I)(17-allyl-1, 14-
dihydroxy-12-[2-(4-hydroXy-3-methoxycy cloheXyl)-1-methyvinyl]-23, 25-dimethoXy-13, 19 …

Purification of rapamycin derivatives using temperature induced phase separation

MW Kayo, RS Fornicola, I Kovacik, L Kondaveti… - US Patent …, 2023 - Google Patents
US11780850B2 - Purification of rapamycin derivatives using temperature induced phase
separation - Google Patents US11780850B2 - Purification of rapamycin derivatives using …

Purification method of lactone compounds containing unsaturated alkyl group by extraction with silver ion solution

JJ Kim, SK Lim, MO Lee, SM Lim, B Lee… - US Patent …, 2012 - Google Patents
This application is a continuation application under 35 USC S365 (c) of International
Application No. PCT/KR2009/004325, filed Aug. 3, 2009 designating the United States. The …