Actin cytoskeleton dynamics play vital roles in most forms of intracellular trafficking by
promoting the biogenesis and transport of vesicular cargoes. Mounting evidence indicates …

Eukaryotic cells contain various Ca2+-effector proteins that mediate cellular responses to
changes in intracellular Ca2+ levels. A unique class of these proteins—annexins—can bind …

Abstract IL‐22 is an IFN–IL‐10 cytokine family member, which is produced by activated Th1
and NK cells and acts primarily on epithelial cells. Here we demonstrate that IL‐22, in …

Annexins constitute an evolutionary conserved multigene protein superfamily characterized
by their ability to interact with biological membranes in a calcium dependent manner. They …

Disruption of the plasma membrane often accompanies cellular injury, and in muscle,
plasma membrane resealing is essential for efficient recovery from injury. Muscle …

Virions are thought to contain all the essential proteins that govern virus egress from the host
cell and initiation of replication in the target cell. It has been known for some time that …

Skeletal cells control the initiation of mineralization in vivo and determine the selective
distribution pattern of mineralization by releasing calcification-initiating, submicroscopic …

In this article, we review the clinical aspects of imaging with the programmed cell–detecting
protein annexin A5 (anxA5). AnxA5 binds to phosphatidylserine, which is one of the “eat me” …

Annexin A2 (AnxA2) is a multifunctional calcium2+ (Ca2+) and phospholipid-binding protein
that is expressed in a wide spectrum of cells, including those participating in the …

This review focuses on the sequence of cellular events leading to calcium signals critical for
phagosome maturation. Immune cells kill microbes by engulfing them in a membrane …