Abstract Properties of responsible for biological activity tetrazoles are considered. Examples
are given of active pharmaceutical ingredients of modern drugs containing the tetrazole ring …

Drugs in the tetrazole series. (Review) Page 1 Chemistry of Heterocyclic Compounds, Vol. 43,
No. 1, 2007 DRUGS IN THE TETRAZOLE SERIES. (REVIEW)* LV Myznikov1, A. Hrabalek2, and …

Tetrazoles are synthetic heterocycles with numerous applications in organic chemistry,
coordination chemistry, the photographic industry, explosives, and, in particular, medicinal …

(S)-Glutamic acid (Glu), which is the main excitatory neurotransmitter in the central nervous
system (CNS), and other excitatory amino acids (EAAs) operate through four different …

Protein tyrosine phosphatases (PTPs) constitute a diverse family of enzymes that, together
with protein tyrosine kinases, control the level of intracellular tyrosine phosphorylation, thus …

Glutamate is the principal excitatory neurotransmitter within the mammalian CNS, playing an
important role in many different functions in the brain such as learning and memory. In this …

Ionotropic glutamate receptors (iGluRs) constitute a family of ligand-gated ion channels that
are essential for mediating fast synaptic transmission in the central nervous system. These …

Glutamic acid (Glu) is the major excitatory neurotransmitter in the mammalian central
nervous system (CNS) where it is involved in the physiological regulation of different …

An efficient synthesis of aryl substituted cyclic sulfonimidamides designed as chiral
nonplanar heterocyclic carboxylic acid bioisosteres is described. The cyclic sulfonimidamide …

A simple, convenient and high-yielding one-pot method for the synthesis of 2-heterocycle-
substituted imidazoles from the corresponding nitriles has been developed. The procedure …