RNA therapeutics offer great potential to transform the biomedical landscape, encompassing
the treatment of hereditary conditions and the development of better vaccines. However, the …

Chemotherapy is a key treatment option for gastric cancer, but over 50% of patients develop
either inherent or acquired resistance to these drugs, resulting in a 5-year survival rate of …

Cathepsin B is a lysosomal cysteine protease, contributing to vital cellular homeostatic
processes including protein turnover, macroautophagy of damaged organelles, antigen …

Small interfering RNA (siRNA) delivery by nanocarriers has been identified as a promising
strategy in the study and treatment of cancer. Short nucleotide sequences are synthesized …

Cancer is a significant health concern, increasingly showing insensitivity to traditional
treatments, highlighting the urgent need for safer and more practical treatment options …

In this study, we analyzed the hepatopancreas tissues of Asian Clam (Corbicula fluminea)
exposed to three different adverse environmental conditions from the same batch using RNA …

RNA interference (RNAi) technology has been a promising treatment strategy for combating
intractable diseases. However, the applications of RNAi in clinical are hampered by …

Melanoma is a common malignant tumor, with a five-year mortality rate as high as 62% in
cases of metastatic melanoma according to cancer statistics (2024). In recent years, the …

Nanoparticles have been crucial in redesigning tumour eradication techniques, and recent
advances in cancer research have accelerated the creation and integration of …

Antiangiogenic therapy with sorafenib (SF) alone is ineffective in eradicating tumors, and its
long-term application can exacerbate tumor hypoxia, which in turn restricts SF's therapeutic …