The process involved in periapical lesions, which occur as an outcome of pulpal necrosis, is
regulated by the immune system including regulatory T cells (Treg) and T helper 17 cell …

Apical periodontitis (AP) is a prevalent infectious and inflammatory disorder that involves
inflammation of periapical tissues and the disintegration of alveolar bone. AP may eventually …

Introduction Dental cysts can be of inflammatory (radicular cysts) or noninflammatory
(dentigerous cysts) origin. Apical periodontitis is a necrosis of the pulp and infection of the …

Abstract Introduction Interleukin (IL)-17+ T-helper (Th17) cells and Foxp3+ regulatory T
(Treg) cells are CD4+ T-helper cells with reciprocal functions in immunology and bone …

Introduction The pathogenesis of periapical lesions is determined by the balance between
host proinflammatory immune response and counteracting anti-inflammatory and reparative …

Abstract Introduction Matrix metalloproteinases (MMPs) are the major class of enzymes
responsible for degradation of extracellular matrix components and participate in the …

Introduction This study assessed the immune-inflammatory profile and the expression of
bone resorption activators receptor activator of nuclear factor kappa B ligand (RANKL) and …

A recently described lineage of lymphocytes, Th17 cells, has been associated with
inflammatory and autoimmune diseases. The aim of this article was to assess the …

Introduction Galectins play important roles in immunoinflammatory responses, but their
participation in the development of periapical lesions remains unclear. This study aimed to …

Abstract Asymptomatic Apical Periodontitis is essentially an inflammatory disease of
microbial aetiology. Association and function of the cell components involved, or specific …