Focal adhesion kinase (FAK) is both a non-receptor tyrosine kinase and an adaptor protein
that primarily regulates adhesion signalling and cell migration, but FAK can also promote …

SOX transcription factors are critical regulators of development, homeostasis and disease
progression and their dysregulation is a common finding in various cancers. SOX9 belongs …

SUMOylation, which is a type of post-translational modification that involves covalent
conjugation of small ubiquitin-like modifier (SUMO) proteins to target substrates, regulates …

Although oncogenicity of the stem cell regulator SOX9 has been implicated in many solid
tumors, its role in lymphomagenesis remains largely unknown. In this study, SOX9 was …

BACKGROUND Insight into the mode of action of plant‐derived acaricides will help in the
development of sustainable control strategies for mite pests. Scopoletin, a promising plant …

Metabolic reprogramming is the survival rule of tumor cells, and tumor cells can meet their
high metabolic requirements by changing the energy metabolism mode. Metabolic …

The role of cancer stem cells (CSCs) in cancer incidence, drug resistance, and relapse after
chemotherapy has been discussed and it has been confirmed that CSCs are extremely …

Primary Sjögren's syndrome (pSS) is a complex autoimmune disease characterized by
lymphocytic infiltration and exocrine dysfunction, particularly affecting the salivary gland …

Hepatocellular carcinoma (HCC), as the most prevalent liver malignancy, is annually
diagnosed in more than half a million people worldwide. HCC is strongly associated with …

Breast cancer (BC) is one of the most common cancers diagnosed and the leading cause of
cancer-related death in women. Although there are first-line treatments for BC, drug …