Vascular anomalies include various diseases, which are classified into two types according
to the International Society for the Study of Vascular Anomalies (ISSVA) classification …

Soft tissue tumors are a relatively rare and diagnostically challenging group of neoplasms
that can have varying lines of differentiation. Accurate diagnosis is important for appropriate …

Vascular and lymphatic malformations represent a challenge for clinicians. The identification
of inherited and somatic mutations in important signaling pathways, including the PI3K …

The fifth edition of the World Health Organization (WHO) classification of soft tissue and
bone tumours was published in May 2020. This 'Blue Book', which is also available digitally …

Identifying genes and variants contributing to rare disease phenotypes and Mendelian
conditions informs biology and medicine, yet potential phenotypic consequences for …

Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm with high morbidity
and mortality. The initiating mechanism during the pathogenesis of KHE has yet to be …

Arteriovenous malformation (AVM) is a fast-flow, congenital vascular anomaly that may arise
anywhere in the body. AVMs typically progress, causing destruction of surrounding tissue …

Vascular malformations are inborn errors of vascular morphogenesis and consist of
localized networks of abnormal blood and/or lymphatic vessels with weak endothelial cell …

Purpose Kaposiform lymphangiomatosis (KLA) is a rare, frequently aggressive, systemic
disorder of the lymphatic vasculature, occurring primarily in children. Even with multimodal …

Vascular anomalies, characterized by the abnormal development or growth of blood and/or
lymphatic vessels, comprise a spectrum of diseases that have a wide range of complications …