The ability of 2-deoxy-d-glucose (2-DG) to interfere with d-glucose metabolism demonstrates
that nutrient and energy deprivation is an efficient tool to suppress cancer cell growth and …

Breast cancer is the most frequent cancer in women and it is the main reason of cancer-
related deaths of women worldwide. Different types of breast cancer diagnostic …

Due to limited availability of pharmacological therapies, triple-negative breast cancer
(TNBC) is the subtype with worst outcome. We hypothesised that 2-Deoxy-D-Glucose (2 …

Synergistic chemotherapy and photothermal therapy (PTT) have emerged as a promising
anticancer paradigm to achieve expected therapeutic effects while mitigating side effects …

Anthracycline antibiotic doxorubicin (DOX) belongs among the most important
antineoplastics used in cancer therapy. Unfortunately, its cytostatic effect in therapeutic …

2-DG, is known as a tumor sensitizer to irradiation (IR) and chemotherapy, which help
improve the treatment rates. It enhances the cytotoxicity via oxidative stress, which is more …

The nonmetabolizable glucose analog 2‐deoxy‐D‐glucose (2‐DG) has shown promising
pharmacological activities, including inhibition of cancerous cell growth and N …

Radiolabeled drug nanocarriers that can be easily imaged via positron emission
tomography (PET) are highly significant as their in vivo outcome can be quantitatively PET …

Introduction Nanoparticles are promising as a new approach to enhance chemo-
radiotherapy efficiency in breast cancer mainly via targeted therapy. Materials & methods …

Abstract Purpose: Two-deoxy-d-glucose (2DG) causes cytotoxicity in the cancer cells by
disrupting the thiol metabolism, and MLN4924 inactivates the SCF E3 ligase and so causes …