Cancer‐related somatic mutations alter adenosine A1 receptor pharmacology—A focus on mutations in the loops and C‐terminus

X Wang, W Jespers, JJ de Waal, KAN Wolff… - The FASEB …, 2022 - Wiley Online Library
G protein‐coupled receptors (GPCRs) are known to be involved in tumor progression and
metastasis. The adenosine A1 receptor (A1AR) has been detected to be over‐expressed in …

Role of A1 adenosine receptor in survival of human lung cancer

E Asgharkhah, MS Jazi, J Asadi, SM Jafari - Gene Reports, 2022 - Elsevier
Adenosine, as a purine nucleoside, has a crucial role in the tumorigenesis through
interaction with adenosine receptors subtypes A1, A2a, A2b, and A3. The role of A1 …