Photodynamic and photothermal therapies: synergy opportunities for nanomedicine

M Overchuk, RA Weersink, BC Wilson, G Zheng - ACS nano, 2023 - ACS Publications
Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …

Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Second near-infrared photothermal materials for combinational nanotheranostics

C Xu, K Pu - Chemical Society Reviews, 2021 - pubs.rsc.org
Second near-infrared photothermal therapy (NIR-II PTT, 1000–1500 nm) has recently
emerged as a new phototherapeutic modality with the advantages of deeper penetration …

Thermal immuno-nanomedicine in cancer

Z Yang, D Gao, J Zhao, G Yang, M Guo… - Nature Reviews …, 2023 - nature.com
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

Solutions to the drawbacks of photothermal and photodynamic cancer therapy

X Deng, Z Shao, Y Zhao - Advanced Science, 2021 - Wiley Online Library
Phototherapy such as photothermal therapy and photodynamic therapy in cancer treatment
has been developed quickly over the past few years for its noninvasive nature and high …

Ultrasound-augmented mitochondrial calcium ion overload by calcium nanomodulator to induce immunogenic cell death

P Zheng, B Ding, Z Jiang, W Xu, G Li, J Ding… - Nano letters, 2021 - ACS Publications
Immunogenic cell death (ICD), a manner of tumor cell death that can trigger antitumor
immune responses, has received extensive attention as a potential synergistic modality for …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Near-infrared photoactivated nanomedicines for photothermal synergistic cancer therapy

H Sun, Q Zhang, J Li, S Peng, X Wang, R Cai - Nano Today, 2021 - Elsevier
Cancer nanomedicines have provided promising treatment strategies for the regression of
several types of cancer, although there still exists a need for significant advances to improve …

Temperature-sensitive lipid-coated carbon nanotubes for synergistic photothermal therapy and gene therapy

Y Zhao, T Zhao, Y Cao, J Sun, Q Zhou, H Chen… - ACS …, 2021 - ACS Publications
The combination of photothermal therapy (PTT) and gene therapy (GT) shows great
potential to achieve synergistic anti-tumor activity. However, the lack of a controlled release …