Systems biology of malaria explored with nonhuman primates

MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum

BE Barber, AN Abd-Rahman, R Webster… - Clinical Infectious …, 2023 - academic.oup.com
Background The long-acting 8-aminoquinoline tafenoquine may be a good candidate for
mass drug administration if it exhibits sufficient blood-stage antimalarial activity at doses low …

Sterile protection against P. vivax malaria by repeated blood stage infection in the Aotus monkey model

N Obaldía, JL Da Silva Filho, M Núñez… - Life Science …, 2024 - life-science-alliance.org
The malaria parasite Plasmodium vivax remains a major global public health challenge, and
no vaccine is approved for use in humans. Here, we assessed whether P. vivax strain …

Epidemiological characteristics of P. vivax asymptomatic infections in the Peruvian Amazon

E Villasis, SS Garcia Castillo, M Guzman… - Frontiers in cellular …, 2022 - frontiersin.org
Introduction Herein, we tested the hypothesis that Asymptomatic P. vivax (Pv) infected
individuals (Asym) feature different epidemiological, clinical and biochemical characteristics …

Transmission Blocking Activity of Low-dose Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum

R Webster, H Mitchell, JM Peters… - Clinical Infectious …, 2023 - academic.oup.com
Background Blocking the transmission of parasites from humans to mosquitoes is a key
component of malaria control. Tafenoquine exhibits activity against all stages of the malaria …

[HTML][HTML] Characterising the blood-stage antimalarial activity of pyronaridine in healthy volunteers experimentally infected with Plasmodium falciparum

BE Barber, R Webster, AJ Potter, S Llewellyn… - International Journal of …, 2024 - Elsevier
With the spread of artemisinin resistance throughout Southeast Asia and now in Africa, the
antimalarial drug pyronaridine is likely to become an increasingly important component of …

Introduction: An Overview of Malaria and Plasmodium

M Anwar - Drug Targets for Plasmodium Falciparum: Historic to …, 2024 - Springer
Malaria is a terrible infectious disease that affects people all over the world. Because it is so
common in economically developing regions' poorer countries, it poses serious clinical and …

Sterile protection against Plasmodium vivax malaria by repeated blood stage infection in a non-human primate model

N Obaldía III, JL Da Silva Filho, M Núñez, KA Glass… - bioRxiv, 2023 - biorxiv.org
The malaria parasite Plasmodium vivax remains a major global public health challenge,
causing major morbidity across tropical and subtropical regions. Several candidate vaccines …

[PDF][PDF] MAJOR ARTICLE

BE Barber, AN Abd-Rahman, R Webster, AJ Potter… - 2023 - media.malariaworld.org
Background: The long acting 8-aminoquinoline tafenoquine may be a good candidate for
mass drug administration if it exhibits sufficient blood stage antimalarial activity at doses low …

[PDF][PDF] Estudio de infecciones asintomáticas por Plasmodium vivax en la Amazonía peruana a nivel epidemiológico y de respuesta inmune de anticuerpos

EMV MAYURI, E Melisa - repositorio.upch.edu.pe
FIGURA 6. Lista de antígenos de merozoítos de P. falciparum que se unen a la proteína de
complemento C1q vía anticuerpos y que estuvieron asociadas significativamente con …