Animal models of acute lung injury

G Matute-Bello, CW Frevert… - American Journal of …, 2008 - journals.physiology.org
Acute lung injury in humans is characterized histopathologically by neutrophilic alveolitis,
injury of the alveolar epithelium and endothelium, hyaline membrane formation, and …

Surfactant therapy for acute lung injury and acute respiratory distress syndrome

K Raghavendran, D Willson… - Critical care …, 2011 - criticalcare.theclinics.com
The extensive pulmonary alveolar and capillary networks make the lungs highly susceptible
to cell and tissue injury from pathogens or toxic environmental agents present either in the …

[图书][B] Lung surfactants: basic science and clinical applications

RH Notter - 2000 - api.taylorfrancis.com
Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Pharmacotherapy of acute lung injury and acute respiratory distress syndrome

K Raghavendran, GS Pryhuber… - Current medicinal …, 2008 - ingentaconnect.com
Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) are
characterized by rapid-onset respiratory failure following a variety of direct and indirect …

Severe meconium aspiration syndrome is not caused by aspiration of meconium

A Ghidini, CY Spong - American journal of obstetrics and gynecology, 2001 - Elsevier
Meconium aspiration syndrome can present clinically with different degrees of severity,
ranging from a mild form of respiratory compromise to severe forms that may result in …

A multicenter, randomized, controlled trial comparing Surfaxin (Lucinactant) lavage with standard care for treatment of meconium aspiration syndrome

TE Wiswell, GR Knight, NN Finer, SM Donn… - …, 2002 - publications.aap.org
Objective. Infants with meconium aspiration syndrome (MAS) have marked surfactant
dysfunction. Airways and alveoli of affected neonates contain meconium, inflammatory cells …

Hypoxic respiratory failure in the late preterm infant

GG Dudell, L Jain - Clinics in Perinatology, 2006 - perinatology.theclinics.com
They have been aptly called the great imposters; late preterm infants (also called near-term)
often are passed off as mature infants, but manifest signs of physiologic immaturity or …

Randomized controlled trial of lung lavage with dilute surfactant for meconium aspiration syndrome

PA Dargaville, B Copnell, JF Mills, I Haron… - The Journal of …, 2011 - Elsevier
OBJECTIVE: To evaluate whether lung lavage with surfactant changes the duration of
mechanical respiratory support or other outcomes in meconium aspiration syndrome (MAS) …

Bronchopulmonary Segmental Lavage with Surfaxin (KL4-Surfactant) for Acute Respiratory Distress Syndrome

TE Wiswell, RM Smith, LB Katz… - American journal of …, 1999 - atsjournals.org
We performed a trial to assess the safety and tolerability of sequential bronchopulmonary
segmental lavage with a dilute synthetic surfactant (Surfaxin) in 12 adults with ARDS …

Resistance of different surfactant preparations to inactivation by meconium

E Herting, P Rauprich, G Stichtenoth, G Walter… - Pediatric …, 2001 - nature.com
A disease similar to acute respiratory distress syndrome may occur in neonates after
aspiration of meconium. The aim of the study was to compare the inhibitory effects of human …