Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 …

GR Thompson, A Soriano, OA Cornely, BJ Kullberg… - The Lancet, 2023 - thelancet.com
Background Rezafungin is a next-generation, once-a-week echinocandin in development
for the treatment of candidaemia and invasive candidiasis and for the prevention of invasive …

Increased incidence of candidemia in a tertiary care hospital with the COVID‐19 pandemic

M Nucci, G Barreiros, LF Guimarães… - Mycoses, 2021 - Wiley Online Library
Background The incidence of candidemia in our hospital has been stable over an 18‐year
period (1.3 episodes per 1000 admissions). Since March 2020, we have observed an …

Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria

RA Drummond, JV Desai, EE Ricotta, M Swamydas… - Cell host & …, 2022 - cell.com
Antibiotics are a modifiable iatrogenic risk factor for the most common human nosocomial
fungal infection, invasive candidiasis, yet the underlying mechanisms remain elusive. We …

Isavuconazole: mechanism of action, clinical efficacy, and resistance

M Ellsworth, L Ostrosky-Zeichner - Journal of fungi, 2020 - mdpi.com
Increasing incidence of invasive fungal infections combined with a growing population of
immunocompromised hosts has created a rising need for antifungal agents. Isavuconazole …

Candida parapsilosis complex in the clinical setting

M Govrins, C Lass-Flörl - Nature Reviews Microbiology, 2024 - nature.com
Representatives of the Candida parapsilosis complex are important yeast species causing
human infections, including candidaemia as one of the leading diseases. This complex …

[HTML][HTML] Rosmarinic acid–modes of antimicrobial and antibiofilm activities of a common plant polyphenol

M Ivanov, M Kostić, D Stojković, M Soković - South African Journal of …, 2022 - Elsevier
Emerging antimicrobial resistance and side effects associated with antibiotics overuse are
driving the need for the novel antimicrobial therapeutics with the natural compounds …

Interplay between Candida albicans and lactic acid bacteria in the gastrointestinal tract: impact on colonization resistance, microbial carriage, opportunistic infection …

KD Zeise, RJ Woods, GB Huffnagle - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Emerging studies have highlighted the disproportionate role of Candida albicans in
influencing both early community assembly of the bacterial microbiome and dysbiosis during …

The interplay between gut bacteria and the yeast Candida albicans

JC Pérez - Gut Microbes, 2021 - Taylor & Francis
The fungus Candida albicans is a ubiquitous member of the human gut microbiota.
Hundreds or thousands of bacterial taxa reside together with this fungus in the intestine …