Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …

Reactive oxygen species (ROS) are fundamental for macrophages to eliminate invasive
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …

Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …

Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …

This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Metabolic pathways and redox reactions are at the core of life. In the past decade (s),
numerous discoveries have shed light on how metabolic pathways determine the cellular …

Ferroptosis (FPT) is a form of cell death due to missed control of membrane lipid
peroxidation (LPO). According to the axiomatic definition of non-accidental cell death, LPO …

Blood protein extravasation through a disrupted blood–brain barrier and innate immune
activation are hallmarks of neurological diseases and emerging therapeutic targets …

Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …