Controversies in the identification and management of acute pulmonary hypertension in preterm neonates

RE Giesinger, K More, J Odame, A Jain, RP Jankov… - Pediatric …, 2017 - nature.com
It is increasingly recognized that the abnormal physiologic consequences of pulmonary
hypertension (PH) may contribute to poor cardiopulmonary health in premature babies …

Pharmacotherapy for pulmonary hypertension in infants with bronchopulmonary dysplasia: Past, present, and future

CD Fike, JL Aschner - Pharmaceuticals, 2023 - mdpi.com
Approximately 8–42% of premature infants with chronic lung disease of prematurity,
bronchopulmonary dysplasia (BPD), develop pulmonary hypertension (PH). Infants with …

[HTML][HTML] Pediatric pulmonary hypertension: definitions, mechanisms, diagnosis, and treatment

D Mukherjee, GG Konduri - Comprehensive Physiology, 2021 - ncbi.nlm.nih.gov
Pediatric pulmonary hypertension (PPH) is a multifactorial disease with diverse etiologies
and presenting features. Pulmonary hypertension (PH), defined as elevated pulmonary …

Sildenafil for pulmonary hypertension in neonates: An updated systematic review and meta‐analysis

Z He, S Zhu, K Zhou, Y Jin, L He, W Xu… - Pediatric …, 2021 - Wiley Online Library
Objectives To provide an updated review and meta‐analysis on the efficacy and safety of
sildenafil for treating persistent pulmonary hypertension in neonates (PPHN). Methods …

[PDF][PDF] Pulmonary vasodilator therapy in persistent pulmonary hypertension of the newborn

M Sharma, E Callan, GG Konduri - Clinics in Perinatology, 2022 - Elsevier
Background PPHN is often a complication of many lung diseases and systemic disorders
that lead to elevated PVR. 1, 2 The fetal pulmonary circulation is characterized by elevated …

Iloprost drug delivery during infant conventional and high-frequency oscillatory ventilation

RM DiBlasi, DN Crotwell, S Shen… - Pulmonary …, 2016 - journals.sagepub.com
Iloprost is a selective pulmonary vasodilator approved for inhalation by the Food and Drug
Administration. Iloprost has been increasingly used in the management of critically ill …

Iloprost attenuates hyperoxia-mediated impairment of lung development in newborn mice

N Olave, CV Lal, B Halloran… - … of Physiology-Lung …, 2018 - journals.physiology.org
Cyclooxygenase-2 (COX-2/PTGS2) mediates hyperoxia-induced impairment of lung
development in newborn animals and is increased in the lungs of human infants with …

Effects of inhaled iloprost for the management of persistent pulmonary hypertension of the newborn

S Verma, R Lumba, SH Kazmi, MJ Vaz… - American journal of …, 2022 - thieme-connect.com
Objective The study aimed to evaluate the effects of inhaled iloprost on oxygenation indices
in neonates with persistent pulmonary hypertension of the newborn (PPHN). Study Design …

[HTML][HTML] 经鼻同步间歇指令通气在重度呼吸窘迫综合征早产儿撤机后的应用

陶海峰, 陶敏, 蔡娜, 廖伟 - Chinese Journal of Contemporary …, 2016 - ncbi.nlm.nih.gov
经鼻同步间歇指令通气在重度呼吸窘迫综合征早产儿撤机后的应用- PMC Back to Top Skip to
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Inhaled iloprost is an effective alternative therapy for persistent pulmonary hypertension in newborns

Ş Yıldırım - Pulmonary Circulation, 2023 - Wiley Online Library
Persistent pulmonary hypertension of the newborn (PPHN) is one of the diseases of the
neonate with severe potential morbidity and mortality. Inhaled iloprost, a stable prostacyclin …