Benchmark guideline for urinary 1-hydroxypyrene as biomarker of occupational exposure to polycyclic aromatic hydrocarbons

FJ Jongeneelen - Annals of occupational Hygiene, 2001 - academic.oup.com
Many individual polycyclic aromatic hydrocarbons (PAH) are genotoxic carcinogens. One of
the parent PAH, pyrene, undergoes simple metabolism to 1-hydroxypyrene. 1 …

Biomonitoring of polycyclic aromatic hydrocarbons in human urine

J Jacob, A Seidel - Journal of Chromatography B, 2002 - Elsevier
Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the
method of choice to determine occupational and/or environmental exposure of an individual …

Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers

G St. Helen, ML Goniewicz, D Dempsey… - Chemical research in …, 2012 - ACS Publications
Our study objectives were (1) to investigate the selectivity of polycyclic aromatic hydrocarbon
(PAH) metabolites for tobacco smoke exposure and (2) to determine half-lives of PAH …

Biomarkers for polycyclic aromatic hydrocarbons in human excreta: recent advances in analytical techniques—a review

K Styszko, J Pamuła, A Pac… - … Geochemistry and Health, 2023 - Springer
Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants that are
generated by the incomplete combustion of organic materials. The main anthropogenic …

[HTML][HTML] A proposal for assessing study quality: Biomonitoring, Environmental Epidemiology, and Short-lived Chemicals (BEES-C) instrument

JS LaKind, JR Sobus, M Goodman, DB Barr… - Environment …, 2014 - Elsevier
The quality of exposure assessment is a major determinant of the overall quality of any
environmental epidemiology study. The use of biomonitoring as a tool for assessing …

Environmental and biological monitoring of exposures to PAHs and ETS in the general population

NJ Aquilina, JM Delgado-Saborit, C Meddings… - Environment …, 2010 - Elsevier
The objective of this study was to analyse environmental tobacco smoke (ETS) and PAH
metabolites in urine samples of non-occupationally exposed non-smoker adult subjects and …

Urinary metabolites of polycyclic aromatic hydrocarbons in relation to idiopathic male infertility

Y Xia, P Zhu, Y Han, C Lu, S Wang, A Gu… - Human …, 2009 - academic.oup.com
BACKGROUND Limited studies have suggested that male reproductive function might be
associated with exposure to polycyclic aromatic hydrocarbons (PAHs). METHODS Five …

Urinary 1-hydroxypyrene as a biomarker of exposure to polycyclic aromatic hydrocarbons: biological monitoring strategies and methodology for determining biological …

MBC VIAU - Biomarkers, 1999 - Taylor & Francis
This article reviews the published studies on urinary 1-hydroxypyrene (1-OHP) as a
biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs) in work environments …

Relation between urinary metabolites of polycyclic aromatic hydrocarbons and human semen quality

Y Xia, Y Han, P Zhu, S Wang, A Gu… - … science & technology, 2009 - ACS Publications
Most of the general populations are exposed to polycyclic aromatic hydrocarbons (PAHs) at
different levels. A limited number of studies have suggested that PAHs exposure may be …

r- 1,t-2,3,c-4-Tetrahydroxy-1,2,3,4-tetrahydrophenanthrene in Human Urine: A Potential Biomarker for Assessing Polycyclic Aromatic Hydrocarbon …

SS Hecht, M Chen, H Yagi, DM Jerina… - … Biomarkers & Prevention, 2003 - AACR
Individual differences in the metabolic activation and detoxification of carcinogenic
polycyclic aromatic hydrocarbons (PAHs) may influence cancer risk. This has been …