Understanding cancer and the anticancer activities of naphthoquinones–a review

KW Wellington - RSC advances, 2015 - pubs.rsc.org
The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

[HTML][HTML] An overview on the antibacterial properties of juglone, naphthazarin, plumbagin and lawsone derivatives and their metal complexes

C Majdi, V Duvauchelle, P Meffre… - Biomedicine & …, 2023 - Elsevier
Bacterial resistance development represents a serious threat to human health across the
globe and has become a very serious clinical problem for many classes of antibiotics …

Discovery of anilino-1, 4-naphthoquinones as potent EGFR tyrosine kinase inhibitors: synthesis, biological evaluation, and comprehensive molecular modeling

P Mahalapbutr, R Leechaisit, A Thongnum… - ACS …, 2022 - ACS Publications
Epidermal growth factor receptor (EGFR) has been recognized as one of the attractive
targets for anticancer drug development. Herein, a set of anilino-1, 4-naphthoquinone …

A comprehensive review on synthesis, biological profile and photophysical studies of heterocyclic compounds derived from 2, 3-diamino-1, 4-naphthoquinone

M Devi, P Kumar, R Singh, L Narayan, A Kumar… - Journal of Molecular …, 2022 - Elsevier
Abstract The 1, 4-naphthoquinone skeleton is an important pharmacophoric unit found in
many biologically active natural products and many well-known chemotherapy agents, such …

Synthesis and biological activity of imidazole based 1, 4-naphthoquinones

D Choudhari, S Salunke-Gawali… - New Journal of …, 2020 - pubs.rsc.org
Design and development of drugs in multi-drug resistant (MDR) infections have been of
growing interest. We report the syntheses, and antibacterial and antifungal activities of …

Molecular docking and anticancer activity of some synthesized 1, 4-naphthoquinone derivatives against human cancer cell line

AAS Abdelaziz, M Nawaz, I Izzeldin… - Journal of Molecular …, 2023 - Elsevier
Abstract A series of 2-amino-4H-naphthopyran-3-carbonitrile (1–16a) derivatives and 2-
amino-4H-naphthopyran-3-carbonitrile (17–19b) derivatives were synthesized and were …

Sulforaphane regulates phenotypic and functional switching of both induced and spontaneously differentiating human monocytes

S Pal, VB Konkimalla - International immunopharmacology, 2016 - Elsevier
At the site of inflammation, switching default on polarization of monocyte differentiation into
classically activated macrophages (M1 type) is one of the pathogenic outcomes in several …

Novel 2-amino-1, 4-naphthoquinone hybrids: Design, synthesis, cytotoxicity evaluation and in silico studies

M Gholampour, H Seradj, S Pirhadi… - Bioorganic & Medicinal …, 2020 - Elsevier
In the present work, a novel series of 2-amino-1, 4-naphthoquinones bearing oxyphenyl
moiety (5a-5m) were designed and synthesized via a two-step route and evaluated for their …

Aminonaphthoquinones as photosensitizers for mesoporous ZnO based dye-sensitized solar cells

SA Mahadik, HM Pathan, S Salunke-Gawali… - Journal of Alloys and …, 2020 - Elsevier
Dye-sensitized solar cells (DSSCs) were fabricated on mesoporous ZnO using different
novel 2R-(n-alkylamino)-1, 4-naphthoquinone photosensitizers, viz; HA3;(2-propylamine-1 …

Novel 2-Amino-1, 4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy

HY Tan, FM Liang, WJ Zhang, Y Zhang, JH Cui, YY Dai… - Molecules, 2023 - mdpi.com
A series of 1, 4-naphthoquinone derivatives containing were synthesized as anti-cancer
agents and the crystal structure of compound 5a was confirmed by X-ray diffraction. In …