Microbial communities inhabit our entire planet and have a crucial role in biogeochemical
processes, agriculture, biotechnology, and human health. Here, we argue that 'in situ …

Our understanding of bacterial pathogenesis is dominated by the cell biology of the host–
pathogen interaction. However, the majority of metabolites that are used in prokaryotic and …

The extent to which microorganisms impair wound healing is an ongoing controversy in the
management of chronic wounds. Because the high diversity and extreme variability of the …

"… a number of chapters provide excellent summaries of the modern methods available for
studying fungal ecology, along with those more traditional methods that are still extremely …

The endoplasmic reticulum (ER) is the major organelle in the cell for protein folding and
plays an important role in cellular functions. The unfolded protein response (UPR) is …

Pore-forming toxins (PFTs) are key virulence determinants produced and secreted by a
variety of human bacterial pathogens. They disrupt the plasma membrane (PM) by …

The interaction between host and pathogen decidedly shapes the outcome of an infection,
thus understanding this interaction is critical to the treatment of a pathogen-induced …

Quorum sensing (QS) is a widespread phenomenon in the microbial world that has
important implications in the coordination of population-wide responses in several bacterial …

Metabolism underpins the physiology and pathogenesis of Mycobacterium tuberculosis.
However, although experimental mycobacteriology has provided key insights into the …

Antibiotic therapy and host cells frequently fail to eliminate invasive bacterial pathogens due
to the emergence of antibiotic resistance, resulting in the relapse and recurrence of …