The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

The sulfur biochemistry of the thiol group endows cysteines with a number of highly
specialized and unique features that enable them to serve a variety of different functions in …

Hydrogen peroxide (H2O2) is an important metabolite involved in most of the redox
metabolism reactions and processes of the cells. H2O2 is recognized as one of the main …

Over the last decade, a dual character of cell response to oxidative stress, eustress versus
distress, has become increasingly recognized. A growing body of evidence indicates that …

Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …

Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …

Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that
reduce peroxides, with a conserved cysteine residue, designated the “peroxidatic” Cys (CP) …

Incomplete reduction of oxygen produces reactive oxygen species (ROS) or intermediates.
Hydrogen peroxide (H 2 O 2), superoxide (O 2•−), hydroxyl radical (• OH), and hypochlorite …

Abstract Hydrogen peroxide (H2O2) acts as a signaling messenger by triggering the
reversible oxidation of redox-regulated proteins. It remains unclear how proteins can be …

Hydrogen peroxide (H2O2), a non-radical reactive oxygen species generated during many
(patho) physiological conditions, is currently universally recognized as an important …