Heat shock protein 90 (Hsp90) is a molecular chaperone that is involved in the activation of
disparate client proteins. This implicates Hsp90 in diverse biological processes that require …

Photodynamic therapy (PDT) has been known for over a hundred years, but is only now
becoming widely used. Originally developed as a tumor therapy, some of its most successful …

The ubiquitous molecular chaperone Hsp90 makes up 1–2% of cytosolic proteins and is
required for viability in eukaryotes. Hsp90 affects the folding and activation of a wide variety …

Molecular chaperones, as the name suggests, are involved in folding, maintenance,
intracellular transport, and degradation of proteins as well as in facilitating cell signaling …

On the surface heat shock protein 90 (Hsp90) is an unlikely drug target for the treatment of
any disease, let alone cancer. Hsp90 is highly conserved and ubiquitously expressed in all …

Background Emerging studies indicate that hypericin has diverse pharmacological actions
and exhibits potential for treatment of various types of cancer. Purpose The current review …

Hypericin (4, 5, 7, 4′, 5′, 7′-hexahydroxy-2, 2′-dimethylnaphtodianthrone) is a naturally
occurring chromophore found in some species of the genus Hypericum, especially …

Abstract The 90-kiloDalton (kD) heat shock protein (Hsp90) is a ubiquitous, ATP-dependent
molecular chaperone whose primary function is to ensure the proper folding of several …

The molecular chaperone Hsp90 has emerged as an important target in cancer treatment
because of its roles in maintaining transformation and regulating the function of proteins …

Hypericin, an extract from St John's Wort (Hypericum perforatum L.), is a promising
photosensitizer in the context of clinical photodynamic therapy due to its excellent …