The involvement of exosomes in the diagnosis and treatment of pancreatic cancer

AN Ariston Gabriel, F Wang, Q Jiao, U Yvette, X Yang… - Molecular cancer, 2020 - Springer
At the moment, pancreatic cancer is among the deadliest gastrointestinal diseases, and
pancreatic cancer growth is a complex biological process that is based on different kinds of …

Prognostic role of the neutrophil-to-lymphocyte ratio in pancreatic cancer: a meta-analysis containing 8252 patients

Y Zhou, Q Wei, J Fan, S Cheng, W Ding, Z Hua - Clinica chimica acta, 2018 - Elsevier
Several studies were carried out to explore the prognostic role of neutrophil-to-lymphocyte
ratio (NLR) in pancreatic cancer, however, with contradictory results. The objectives of this …

Exosomal microRNA in pancreatic cancer diagnosis, prognosis, and treatment: from bench to bedside

MH Uddin, MN Al-Hallak, PA Philip, RM Mohammad… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic cancer is the fourth leading cause of cancer death in the United
States and over 90% of the patients suffer from pancreatic ductal adenocarcinoma (PDAC) …

Consensus statement on mandatory measurements in pancreatic cancer trials (COMM-PACT) for systemic treatment of unresectable disease

E Ter Veer, LB van Rijssen, MG Besselink… - The Lancet …, 2018 - thelancet.com
Variations in the reporting of potentially confounding variables in studies investigating
systemic treatments for unresectable pancreatic cancer pose challenges in drawing …

[HTML][HTML] Differences between KC and KPC pancreatic ductal adenocarcinoma mice models, in terms of their modeling biology and their clinical relevance

ANA Gabriel, Q Jiao, U Yvette, X Yang, SA Al-Ameri… - Pancreatology, 2020 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is among the dangerous human cancers, is the
10th highly prevalent cancer, and the fourth sole cause of cancer-related mortality in the …

[HTML][HTML] Abnormal Histopathological Expression of Klotho, Ferroptosis, and Circadian Clock Regulators in Pancreatic Ductal Adenocarcinoma: Prognostic Implications …

C García-Montero, O Fraile-Martinez, D Cobo-Prieto… - Biomolecules, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal tumor with increasing
incidence, presenting numerous clinical challenges. The histopathological examination of …

Exosomes in the treatment of pancreatic cancer: a moonshot to PDAC treatment?

SP Papadakos, N Dedes, A Pergaris… - International Journal of …, 2022 - mdpi.com
Pancreatic Ductal Adenocarcinoma (PDAC) constitutes a leading cause of cancer death
globally. Its mortality remains unaltered despite the considerable scientific progress made in …

Identification and validation of heterotypic cell-in-cell structure as an adverse prognostic predictor for young patients of resectable pancreatic ductal adenocarcinoma

H Huang, M He, Y Zhang, B Zhang, Z Niu… - … and Targeted Therapy, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with an overall 5-year
survival rate of less than 10%. Between 20 and 30% of PDAC cases are resectable at …

A novel PiRNA enhances CA19-9 sensitivity for pancreatic cancer identification by liquid biopsy

W Li, M Gonzalez-Gonzalez, L Sanz-Criado… - Journal of Clinical …, 2022 - mdpi.com
Pancreatic cancer is one of the deadliest tumours worldwide, and its poor prognosis is due
to an inability to detect the disease at the early stages, thereby creating an urgent need to …

The match between molecular subtypes, histology and microenvironment of pancreatic cancer and its relevance for chemoresistance

J Martinez-Useros, M Martin-Galan, J Garcia-Foncillas - Cancers, 2021 - mdpi.com
Simple Summary Based on the four molecular subtypes of pancreatic cancer described by
Bailey et al. 2016, in the present article we match the molecular, histology and …