Arrhythmogenic Cardiomyopathy (ACM), a Mendelian disorder that can affect both left and
right ventricles, is most often associated with pathogenic desmosomal variants that can lead …

The “Extreme Exercise Hypothesis” states that when individuals perform training beyond the
ideal exercise dose, a decline in the beneficial effects of physical activity occurs. This is due …

Objective To investigate the expression of myocardium connexin 43 (Cx43) in late exercise
preconditioning (LEP) cardioprotection. Methods Eight-week-old adult male Sprague …

Limiting cancer-induced cardiac damage has become an increasingly important issue to
improve survival rates and quality of life. Exercise training has been shown to reduce …

Aerobic exercise training induces a unique cardioprotective phenotype, but it is becoming
clear that it does not promote the same structural, functional, and molecular adaptations in …

Aims: Increasing age is the most important risk factor for atrial fibrillation (AF). Very high
doses of exercise training might increase AF risk, while moderate levels seem to be …

Human cell types affected by retinal diseases (such as age-related macular degeneration or
retinitis pimentosa) are limited in cell number and of reduced accessibility. As a …

Purpose: The aim of this investigation was to assess the influence of an 8-month physical
training period on left ventricular voltages identified by resting ECG in relation to changes in …

Background: Gap Junction (GJ) plays a role in supporting the heart electricity. Connexin43
(Cx43) as the main protein constituent of GJ in left cardiac ventricle, will increase in number …