Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative …

As marijuana use becomes legal in some states, the dominant public opinion is that
marijuana is a harmless source of mood alteration. Although the harms associated with …

In an increasing number of states and countries, cannabis now stands poised to join alcohol
and tobacco as a legal drug. Quantifying the relative adverse and beneficial effects of …

Background Cannabis legalization and increases in cannabis use are occurring rapidly in
the United States (US). Cannabis and tobacco are often used together, but it is unclear …

Background Tobacco and cannabis are among the most commonly used psychoactive
substances worldwide, and are often used in combination. Evidence suggests that tobacco …

Objectives. To estimate changes in the prevalence of daily cannabis use among current,
former, and never cigarette smokers from 2002 to 2014 in the United States. Methods. The …

Background: Based on the prevalence and health implications of tobacco and cannabis use,
aiming to reduce their use, especially among youth, is a sound objective at both the …

There have been dramatic changes worldwide in the attitudes toward and consumption of
recreational and medical cannabis. Cannabinoid receptors, which mediate the actions of …

Abstract Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is
responsible for the drug's reinforcing effects. Retrospective human studies suggest that …

Background Little is known about event-level patterns of marijuana co-or tri-use with alcohol
and tobacco. Thus, the study goal was to examine patterns of same-day alcohol, cigarette …