Cholesterol gallstone formation is a complex process mediated by genetic and
environmental factors. Until recently, the role of the immune system in the pathogenesis of …

Hepatitis C virus infection represents a major problem of public health with around 350
millions of chronically infected individuals worldwide. The frequent evolution towards severe …

BACKGROUND/AIMS: The direct implication of low-density lipoprotein receptor (LDLR) in
hepatitis C virus (HCV) infection of human hepatocyte has not been demonstrated. Normal …

AIM: To explore the status of extrahepatic hepatitis C virus (HCV) infection and replication in
hepatitis C patients, and its potential implication in HCV infection and pathogenicity …

Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide, but the study of HCV
infection has been hampered by the lack of an in vitro or in vivo small animal model. The …

We evaluated the prevalence and the risk factors for gallstone disease in patients with
chronic hepatitis C infection. We investigated 453 consecutively admitted patients with …

The possibility that HCV infects lymphoid cells has been widely discussed. Evidence in favor
of HCV tropism for lymphoid cells derives from a series of data including:(1) the higher …

The detection of markers of hepatitis C virus (HCV) infection is complicated by the presence
of virus in circulating blood. Consequently, it is necessary to target the negative-strand virus …

Understanding the pathogenesis of hepatitis C requires the availability of tissue culture
models that sustain viral replication and produce infectious particles. We report on the …

Gallstones are more common in patients with cirrhosis of the liver, and the incidence
increases with severity of liver disease. Pigment stones are the most frequent type of …