Diabetes Mellitus: a review on pathophysiology, current status of oral pathophysiology, current status of oral medications and future perspectives
Diabetes mellitus (DM), belongs to the class of metabolic diseases which the main symptom
associated with this disease is the high sugar levels in blood for a long period. It can be …
associated with this disease is the high sugar levels in blood for a long period. It can be …
[HTML][HTML] Features and facts of a gastroretentive drug delivery system-a review
K Vinchurkar, J Sainy, MA Khan, M Sheetal… - Turkish journal of …, 2022 - ncbi.nlm.nih.gov
Abstract English oral delivery of drug was the commonly used modality because of patient
compliance and ease of administration. After oral administration of any drug, its …
compliance and ease of administration. After oral administration of any drug, its …
Optimization and in vivo evaluation of triamcinolone acetonide loaded in situ gel prepared using reacted tamarind seed xyloglucan and kappa-carrageenan for ocular …
In the current work, triamcinolone acetonide (TAA) loaded dual responsive in situ gelling
system was designed and optimized using reacted tamarind seed xyloglucan (RXG) …
system was designed and optimized using reacted tamarind seed xyloglucan (RXG) …
[HTML][HTML] Discovery potent of thiazolidinedione derivatives as antioxidant, α-amylase inhibitor, and antidiabetic agent
MY Sameeh, MM Khowdiary, HS Nassar, MM Abdelall… - Biomedicines, 2021 - mdpi.com
This work aimed to synthesize safe antihyperglycemic derivatives bearing thiazolidinedione
fragment based on spectral data. The DFT theory discussed the frontier molecular orbitals …
fragment based on spectral data. The DFT theory discussed the frontier molecular orbitals …
Recent advancements in mucoadhesive floating drug delivery systems: A mini-review
Over the past few decades, extensive research has been carried out to develop a
gastroretentive dosage form (GRDF). This type of dosage form can improve the delivery and …
gastroretentive dosage form (GRDF). This type of dosage form can improve the delivery and …
Evaluation of Ulcer Protective Activity of Morus alba L. Extract‐Loaded Chitosan Microspheres in Ethanol‐Induced Ulcer in Rat Model
Due to an unhealthy lifestyle, gastric ulcers have become a very common disease these
days. Moreover, the side effects linked with the prolonged use of conventional treatments …
days. Moreover, the side effects linked with the prolonged use of conventional treatments …
[HTML][HTML] Okra-Thioglycolic acid conjugate—Synthesis, characterization, and evaluation as a mucoadhesive polymer
The success of mucoadhesive drug delivery systems relies on the type of polymer used,
which becomes adhesive naturally upon hydration. Intended polymers should be able to …
which becomes adhesive naturally upon hydration. Intended polymers should be able to …
Dual crosslinked pectin–alginate network as sustained release hydrophilic matrix for repaglinide
Repaglinide, an oral antidiabetic agent, has a rapid onset of action and short half–life of
approximately 1 h. Developing a controlled and prolonged release delivery system is …
approximately 1 h. Developing a controlled and prolonged release delivery system is …
Phospholipid complex enriched micelles: a novel drug delivery approach for promoting the antidiabetic effect of repaglinide
To enhance the oral antidiabetic effect of repaglinide (RG), a newly emerging approach,
based on the combination of phospholipid complexation and micelle techniques, was …
based on the combination of phospholipid complexation and micelle techniques, was …
[HTML][HTML] Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for …
Duloxetine hydrochloride (DUL) is a BCS class-II antidepressant drug, acting via serotonin
and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited …
and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited …