Acute respiratory distress syndrome (ARDS), a fatal critical disease, is induced by various
insults. ARDS represents a major global public health burden, and the management of …

Simple Summary SARS-CoV-2 caused the COVID-19 health emergency, affecting millions
of people worldwide. Samples collected from hospitalized or dead patients from the early …

BACKGROUND Patients hospitalized for COVID-19 exhibit diverse clinical outcomes, with
outcomes for some individuals diverging over time even though their initial disease severity …

Dexamethasone is the standard of care for critically ill patients with COVID-19, but the
mechanisms by which it decreases mortality and its immunological effects in this setting are …

Viral variant and host vaccination status impact infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), yet how these factors shift cellular responses in the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by highly heterogeneous manifestations ranging from asymptomatic cases to death for still …

Age is a major risk factor for severe coronavirus disease 2019 (COVID-19), yet the
mechanisms behind this relationship have remained incompletely understood. To address …

Secondary bacterial pneumonia (2° BP) is associated with significant morbidity following
respiratory viral infection, yet remains incompletely understood. In a prospective cohort of …

Abstract Coronavirus disease 2019 (COVID-19) poses significant risks for solid organ
transplant recipients, who have atypical but poorly characterized immune responses to …

The glycosylation of IgG plays a critical role during human severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection, activating immune cells and inducing …