Tannins as an alternative to antibiotics

AK Farha, QQ Yang, G Kim, HB Li, F Zhu, HY Liu… - Food Bioscience, 2020 - Elsevier
Excessive use of antibiotics has led to the emergence of multidrug-resistant bacteria that are
a serious threat to human health. There is a need to develop efficient antibacterial agents to …

Tannic acid-based metal phenolic networks for bio-applications: a review

Z Guo, W Xie, J Lu, X Guo, J Xu, W Xu, Y Chi… - Journal of Materials …, 2021 - pubs.rsc.org
Tannic acid (TA), a large polyphenolic molecule, has long been known for use in food
additives, antioxidants, bio-sorbents, animal feed and adhesives due to its intrinsic …

Challenges of intervention, treatment, and antibiotic resistance of biofilm-forming microorganisms

G Gebreyohannes, A Nyerere, C Bii, DB Sbhatu - Heliyon, 2019 - cell.com
Background Biofilms are multicellular communities of microorganisms held together by a self-
produced extracellular matrix. The ability of microbes to form biofilm is a universal …

Quorum sensing signal–response systems in Gram-negative bacteria

K Papenfort, BL Bassler - Nature Reviews Microbiology, 2016 - nature.com
Bacteria use quorum sensing to orchestrate gene expression programmes that underlie
collective behaviours. Quorum sensing relies on the production, release, detection and …

Carboxymethyl chitosan/tannic acid hydrogel with antibacterial, hemostasis, and antioxidant properties promoting skin wound repair

X Zhou, Q Zhou, Q Chen, Y Ma, Z Wang… - ACS Biomaterials …, 2022 - ACS Publications
Local causes of slow wound healing include infection and wound hemorrhage. Using
sodium bicarbonate as a neutralizer, a variety of carboxymethyl chitosan–tannic acid (CMC …

Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors

SAKS Ahmed, M Rudden, TJ Smyth… - Applied microbiology …, 2019 - Springer
At present, anti-virulence drugs are being considered as potential therapeutic alternatives
and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit …

New perspectives on the use of phytochemicals as an emergent strategy to control bacterial infections including biofilms

A Borges, AC Abreu, C Dias, MJ Saavedra, F Borges… - Molecules, 2016 - mdpi.com
The majority of current infectious diseases are almost untreatable by conventional antibiotic
therapy given the advent of multidrug-resistant bacteria. The degree of severity and the …

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections

S Wagner, R Sommer, S Hinsberger, C Lu… - Journal of medicinal …, 2016 - ACS Publications
Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …

Stacking domains and dislocation networks in marginally twisted bilayers of transition metal dichalcogenides

VV Enaldiev, V Zolyomi, C Yelgel, SJ Magorrian… - Physical review …, 2020 - APS
We apply a multiscale modeling approach to study lattice reconstruction in marginally
twisted bilayers of transition metal dichalcogenides (TMD). For this, we develop density …