Neural stem cell metabolism revisited: a critical role for mitochondria

V Scandella, F Petrelli, DL Moore, SMG Braun… - Trends in Endocrinology …, 2023 - cell.com
Metabolism has emerged as a key regulator of stem cell behavior. Mitochondria are crucial
metabolic organelles that are important for differentiated cells, yet considered less so for …

The astrocyte: metabolic hub of the brain

LF Barros, S Schirmeier… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Astrocytic metabolism has taken center stage. Interposed between the neuron and the
vasculature, astrocytes exert control over the fluxes of energy and building blocks required …

Oligodendrocyte-derived transcellular signaling regulates axonal energy metabolism

S Li, ZH Sheng - Current opinion in neurobiology, 2023 - Elsevier
The unique morphology and functionality of central nervous system (CNS) neurons
necessitate specialized mechanisms to maintain energy metabolism throughout long axons …

The gut microbiota‐astrocyte axis: implications for type 2 diabetic cognitive dysfunction

ZH Li, YY Jiang, CY Long, Q Peng… - CNS Neuroscience & …, 2023 - Wiley Online Library
Background Diabetic cognitive dysfunction (DCD) is one of the most insidious complications
of type 2 diabetes mellitus, which can seriously affect the ability to self‐monitoring of blood …

Metabolic homeostasis of tissue macrophages across the lifespan

SK Wculek, S Forisch, V Miguel, D Sancho - Trends in Endocrinology & …, 2024 - cell.com
Macrophages are present in almost all organs. Apart from being immune sentinels, tissue-
resident macrophages (TRMs) have organ-specific functions that require a specialized …

[HTML][HTML] Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial

S Sethi, D Wakeham, T Ketter, F Hooshmand… - Psychiatry …, 2024 - Elsevier
The ketogenic diet (KD, also known as metabolic therapy) has been successful in the
treatment of obesity, type 2 diabetes, and epilepsy. More recently, this treatment has shown …

Immune modulatory effects of ketogenic diet in different disease conditions

S Srivastava, VA Pawar, A Tyagi, KP Sharma, V Kumar… - Immuno, 2022 - mdpi.com
Interceding nutrients have been acquiring increased attention and prominence in the field of
healing and deterrence of various disorders. In this light, the present article encompasses …

The proteomic effects of ketone bodies: implications for proteostasis and brain proteinopathies

L García-Velázquez, L Massieu - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
A growing body of evidence supports the beneficial effects of the ketone bodies (KBs),
acetoacetate and β-hydroxybutyrate (BHB), on diverse physiological processes and …

Metabolic aspects of genetic ion channel epilepsies

ES Neal, W Xu, K Borges - Journal of Neurochemistry, 2024 - Wiley Online Library
Nowadays, particularly in countries with high incomes, individual mutations in people
affected by genetic epilepsies are identified, and genetic therapies are being developed. In …

C1q is increased in cerebrospinal fluid‐derived extracellular vesicles in Alzheimer's disease: A multi‐cohort proteomics and immuno‐assay validation study

M Chatterjee, S Özdemir, M Kunadt… - Alzheimer's & …, 2023 - Wiley Online Library
Abstract Introduction Extracellular vesicles (EVs) may propagate and modulate Alzheimer's
disease (AD) pathology. We aimed to comprehensively characterize the proteome of …