Biomarkers for the progression of intermediate age-related macular degeneration

EM Lad, RP Finger, R Guymer - Ophthalmology and Therapy, 2023 - Springer
Age-related macular degeneration (AMD) is a leading cause of severe vision loss
worldwide, with a global prevalence that is predicted to substantially increase. Identifying …

New insight of metabolomics in ocular diseases in the context of 3P medicine

Q Zhang, N Wang, Y Rui, Y Xia, S Xiong, X Xia - EPMA Journal, 2023 - Springer
Metabolomics refers to the high-through untargeted or targeted screening of metabolites in
biofluids, cells, and tissues. Metabolome reflects the functional states of cells and organs of …

Alterations in Faecal and Serum Metabolic Profiles in Patients with Neovascular Age-Related Macular Degeneration

Q Yuan, S Zhu, S Yue, Y Han, G Peng, L Li, Y Sheng… - Nutrients, 2023 - mdpi.com
Neovascular age-related macular degeneration (nAMD) is a common and multifactorial
disease in the elderly that may lead to irreversible vision loss; yet the pathogenesis of AMD …

Metabolomics in corneal Diseases: a narrative review from clinical aspects

AWJ Teo, J Zhang, L Zhou, YC Liu - Metabolites, 2023 - mdpi.com
Corneal pathologies may have subtle manifestations in the initial stages, delaying diagnosis
and timely treatment. This can lead to irreversible visual loss. Metabolomics is a rapidly …

Metabolomics facilitates differential diagnosis in common inherited retinal degenerations by exploring their profiles of serum metabolites

WC Wang, CH Huang, HH Chung, PL Chen… - Nature …, 2024 - nature.com
The diagnosis of inherited retinal degeneration (IRD) is challenging owing to its phenotypic
and genotypic complexity. Clinical information is important before a genetic diagnosis is …

Dysregulated Arginine Metabolism Is Linked to Retinal Degeneration in Cep250 Knockout Mice

L Xiang, QL Yang, BT Xie, HY Zeng… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: Degeneration of retinal photoreceptors is frequently observed in diverse ciliopathy
disorders, and photoreceptor cilium gates the molecular trafficking between the inner and …

Clinical performance of predicting late age‐related macular degeneration development using multimodal imaging

KL Goh, CJ Abbott, TG Campbell… - Clinical & …, 2024 - Wiley Online Library
Background To examine whether the clinical performance of predicting late age‐related
macular degeneration (AMD) development is improved through using multimodal imaging …

[HTML][HTML] Plasma Metabolites Associated with OCT Features of Age-Related Macular Degeneration

I Lains, X Han, J Gil, J Providencia, A Nigalye… - Ophthalmology …, 2024 - Elsevier
Purpose The most widely used classifications of age-related macular degeneration (AMD)
and its severity stages still rely on color fundus photographs (CFPs). However, AMD has a …

[PDF][PDF] INTERMEDIATE AGE-RELATED MACULAR DEGENERATION–NONINVASIVE MULTIMODAL ANALYSIS AND LONGITUDINAL STUDY

RMRIOP FLORES - 2023 - run.unl.pt
Abstract Age-related Macular Degeneration (AMD) is an important cause of irreversible
visual impairment, secondary to degenerative macular disorder. AMD can compromise …

Diminished Plasma Serotonin and Taurine Levels are a Metabolic Feature of Age-Related Macular Degeneration

B Gerritsen, R Rijken, M Stehouwer… - Available at SSRN … - papers.ssrn.com
Background: Age-related macular degeneration (AMD) is a leading cause of vision loss in
older adults, but its pathogenic mechanisms remain incompletely understood. Emerging …