[PDF][PDF] Deep learning in population genetics

K Korfmann, OE Gaggiotti… - Genome Biology and …, 2023 - academic.oup.com
Population genetics is transitioning into a data-driven discipline thanks to the availability of
large-scale genomic data and the need to study increasingly complex evolutionary …

Inferring balancing selection from genome-scale data

BD Bitarello, DYC Brandt, D Meyer… - Genome biology and …, 2023 - academic.oup.com
The identification of genomic regions and genes that have evolved under natural selection is
a fundamental objective in the field of evolutionary genetics. While various approaches have …

Fluctuating selection and the determinants of genetic variation

OL Johnson, R Tobler, JM Schmidt, CD Huber - Trends in Genetics, 2023 - cell.com
Recent studies of cosmopolitan Drosophila populations have found hundreds to thousands
of genetic loci with seasonally fluctuating allele frequencies, bringing temporally fluctuating …

Balancing selection on genomic deletion polymorphisms in humans

A Aqil, L Speidel, P Pavlidis, O Gokcumen - Elife, 2023 - elifesciences.org
A key question in biology is why genomic variation persists in a population for extended
periods. Recent studies have identified examples of genomic deletions that have remained …

Temporal challenges in detecting balancing selection from population genomic data

V Soni, JD Jensen - G3: Genes, Genomes, Genetics, 2024 - academic.oup.com
The role of balancing selection in maintaining genetic variation remains an open question in
population genetics. Recent years have seen numerous studies identifying candidate loci …

[HTML][HTML] Genomic findings and their implications for the evolutionary social sciences

BP Zietsch - Evolution and Human Behavior, 2024 - Elsevier
What past selection pressures have shaped human traits and their variation and covariation
across individuals? These are key questions in the evolutionary social sciences. Recent …

[HTML][HTML] Balancing selection and the functional effects of shared polymorphism in cryptic Daphnia species

CS Murray, M Karram, DJ Bass, M Doceti, D Becker… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The patterns of genetic variation within and between related taxa represent the genetic
history of a species. Shared polymorphisms, loci with identical alleles across species, are of …

[HTML][HTML] Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

AM Pivirotto, A Platt, R Patel, S Kumar, J Hey - bioRxiv, 2023 - ncbi.nlm.nih.gov
A classic population genetic prediction is that alleles experiencing directional selection
should swiftly traverse allele frequency space, leaving detectable reductions in genetic …

Analyses of allele age and impact reveal human beneficial alleles are older than neutral controls

A Pivirotto, A Platt, R Patel, S Kumar, J Hey - bioRxiv, 2023 - biorxiv.org
A classic population genetic prediction is that alleles experiencing directional selection
should swiftly traverse allele frequency space, leaving detectable reductions in genetic …