Organophosphorus (OP) pesticides and nerve agents still pose a threat to the population.
Treatment of OP poisoning is an ongoing challenge and burden for medical services …

The present review discusses the structure of the anticholinesterase organophosphates
(OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of …

The number of intoxications with organophosphorus pesticides (OPs) is estimated at some 3
000 000 per year, and the number of deaths and casualties some 300 000 per year. OPs act …

The cholinesterase-inhibiting organophosphorus compounds referred to as nerve agents
(soman, sarin, tabun, GF agent, and VX) are particularly toxic and are considered to be …

Organophosphorus compounds (OPs) are used as pesticides and developed as warfare
nerve agents such as tabun, soman, sarin, VX and others. Exposure to even small amounts …

A review was conducted of papers describing the use of N‐methyl‐2‐pyridinealdoxime
(PAM), toxogonin or HI‐6 as antidotes to the nerve agents tabun, sarin, soman and VX. The …

The use of organophosphorus pesticides results in toxicity risk to non-target organisms.
Organophosphorus compounds share a common mode of action, exerting their toxic effects …

Poisoning by organophosphorus pesticides results from inhibition of acetylcholinesterase.
The outcome and optimum treatment depend on properties which differ among individual …

Both organophosphorus (OP) and carbamate insecticides inhibit acetylcholinesterase
(AChE), which results in accumulation of acetylcholine (ACh) at autonomic and some central …

Poisoning by organophosphorus compounds (OP) still is a major therapeutic problem.
Intentional OP pesticide poisoning results in up to 300.000 deaths each year and highly …