Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …
clinic represents the culmination of decades of research. Lying at the convergence of …
Understanding the role of sensorimotor beta oscillations
J Barone, HE Rossiter - Frontiers in Systems Neuroscience, 2021 - frontiersin.org
Beta oscillations have been predominantly observed in sensorimotor cortices and basal
ganglia structures and they are thought to be involved in somatosensory processing and …
ganglia structures and they are thought to be involved in somatosensory processing and …
Neural signatures of hyperdirect pathway activity in Parkinson's disease
Parkinson's disease (PD) is characterised by the emergence of beta frequency oscillatory
synchronisation across the cortico-basal-ganglia circuit. The relationship between the …
synchronisation across the cortico-basal-ganglia circuit. The relationship between the …
Beta oscillations in working memory, executive control of movement and thought, and sensorimotor function
Beta oscillations (∼ 13 to 30 Hz) have been observed during many perceptual, cognitive,
and motor processes in a plethora of brain recording studies. Although the function of beta …
and motor processes in a plethora of brain recording studies. Although the function of beta …
Mechanisms of deep brain stimulation
TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
Beta burst dynamics in Parkinson's disease OFF and ON dopaminergic medication
Exaggerated basal ganglia beta activity (13–35 Hz) is commonly found in patients with
Parkinson's disease and can be suppressed by dopaminergic medication, with the degree of …
Parkinson's disease and can be suppressed by dopaminergic medication, with the degree of …
Cross-frequency coupling and intelligent neuromodulation
Cross-frequency coupling (CFC) reflects (nonlinear) interactions between signals of different
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …
Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …
Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease
C De Hemptinne, NC Swann, JL Ostrem… - Nature …, 2015 - nature.com
Deep brain stimulation (DBS) is increasingly applied for the treatment of brain disorders, but
its mechanism of action remains unknown. Here we evaluate the effect of basal ganglia DBS …
its mechanism of action remains unknown. Here we evaluate the effect of basal ganglia DBS …
Untangling cross-frequency coupling in neuroscience
Highlights•Fundamental caveats and confounds in the methodology of assessing CFC are
discussed.•Significant CFC can be observed without any underlying physiological …
discussed.•Significant CFC can be observed without any underlying physiological …