For many neuromuscular diseases (NMDs), cardiac disease represents a major cause of
morbidity and mortality. The management of cardiac disease in NMDs is made challenging …

Increasing usage of next-generation sequencing techniques pushed during the last decade
cardiogenetic diagnostics leading to the identification of a huge number of genetic variants …

Myofibrillary myopathies (MFM) are hereditary myopathies histologically characterized by
degeneration of myofibrils and aggregation of proteins in striated muscle. Cardiomyopathy is …

Myofibrillar myopathies (MFM) have been described in the mid-1990s as a group of
diseases sharing common histological features, including an abnormal accumulation of …

BAG3 belongs to BAG family of molecular chaperone regulators interacting with HSP70 and
anti-apoptotic protein Bcl-2. It is ubiquitously expressed with strong expression in skeletal …

Background Myofibrillar myopathies (MFM) are a group of phenotypically and genetically
heterogeneous neuromuscular disorders, which are characterized by protein aggregations …

The Caenorhabditis elegans spermatheca is a myoepithelial tube that stores sperm and
undergoes cycles of stretching and constriction as oocytes enter, are fertilized, and exit into …

Myofibrillar myopathies (MFMs) are a group of hereditary neuromuscular disorders sharing
common histological features, such as myofibrillar derangement, Z-disk disintegration, and …

Background and Objectives The diagnostic process for myofibrillar myopathies (MFM) and
distal myopathies (DM) is particularly complex because of the large number of causative …

Myofibrillar myopathies are a genetically diverse group of skeletal muscle disorders, with
distinctive muscle histopathology. Causative mutations have been identified in the genes …