Iodine: Its role in thyroid hormone biosynthesis and beyond

S Sorrenti, E Baldini, D Pironi, A Lauro, V D'Orazi… - Nutrients, 2021 - mdpi.com
The present review deals with the functional roles of iodine and its metabolism. The main
biological function of iodine concerns its role in the biosynthesis of thyroid hormones (THs) …

Commemorating two centuries of iodine research: an interdisciplinary overview of current research

FC Küpper, MC Feiters, B Olofsson… - Angewandte Chemie …, 2011 - Wiley Online Library
Iodine was discovered as a novel element in 1811 during the Napoleonic Wars. To
celebrate the bicentennial anniversary of this event we reflect on the history and highlight …

Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry

FC Küpper, LJ Carpenter… - Proceedings of the …, 2008 - National Acad Sciences
Brown algae of the Laminariales (kelps) are the strongest accumulators of iodine among
living organisms. They represent a major pump in the global biogeochemical cycle of iodine …

Role of iodide metabolism in physiology and cancer

A De la Vieja, P Santisteban - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid
and the subsequent action of these hormones in the organism. I− is principally transported …

Fluoride exposure induces inhibition of sodium/iodide symporter (NIS) contributing to impaired iodine absorption and iodine deficiency: molecular mechanisms of …

DT Waugh - International Journal of Environmental Research and …, 2019 - mdpi.com
The sodium iodide symporter (NIS) is the plasma membrane glycoprotein that mediates
active iodide transport in the thyroid and other tissues, such as the salivary, gastric mucosa …

Cesium in biology, pancreatic cancer, and controversy in high and low radiation exposure damage—scientific, environmental, geopolitical, and economic aspects

S Venturi - International journal of environmental research and …, 2021 - mdpi.com
Radionuclide contamination in terrestrial ecosystems has reached a dangerous level. The
major artificial radionuclide present in the environment is cesium-137 (137-Cs). In humans …

[PDF][PDF] Role of iodine in evolution and carcinogenesis of thyroid, breast and stomach

S Venturi, FM Donati, M Venturi, A Venturi… - Advances in clinical …, 2000 - academia.edu
The authors have hypothesized that dietary iodine (deficiency or excess) is associated with
the development of some gastric and mammary cancers, as it is well-known for thyroid …

A new HPLC method for the detection of iodine applied to natural samples of edible seaweeds and commercial seaweed food products

U Nitschke, DB Stengel - Food Chemistry, 2015 - Elsevier
Rich in micronutrients and considered to contain high iodine levels, seaweeds have multiple
applications as food/supplements and nutraceuticals with potential health implications …

Iodine in evolution of salivary glands and in oral health

S Venturi, M Venturi - Nutrition and health, 2009 - journals.sagepub.com
The authors hypothesize that dietary deficiency or excess of iodine (I) has an important role
in oral mucosa and in salivary glands physiology. Salivary glands derived from primitive I …

Iodine as a potential endocrine disruptor—a role of oxidative stress

M Karbownik-Lewińska, J Stępniak, P Iwan, A Lewiński - Endocrine, 2022 - Springer
Purpose Iodine is an essential micronutrient required for thyroid hormone biosynthesis.
However, overtreatment with iodine can unfavorably affect thyroid physiology. The aim of …