Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that reduces cell injuries
via detoxification of lipid-peroxidation product, 4-hydroxy-2-nonenal (hydroxynonenal). It is …

Several studies suggested the association of COVID-19 with systemic oxidative stress, in
particular with lipid peroxidation and vascular stress. Therefore, this study aimed to evaluate …

Lysosomes are membrane-bound vesicular structures that mediate degradation and
recycling of damaged macromolecules and organelles within the cell. For ensuring the place …

Objectives. Occupational stress and workload are common risk factors among nurses that
increase absenteeism, reduce the quality and quantity of patient care, increase care costs …

Alzheimer's disease, type 2 diabetes, and non-alcoholic steatohepatitis (NASH) constitute
increasingly prevalent disorders. Individuals with type 2 diabetes are well-known to be …

Background Beyond the signature amyloid-beta plaques and neurofibrillary tangles,
Alzheimer's disease (AD) has been shown to exhibit dysregulated metabolic signaling …

Non-alcoholic fatty liver disease (NAFLD) affects up to 20% of the world's population.
Overactivation of the angiotensin receptor type 1 (AT1) contributes to metabolic dysfunction …

Metabolic-associated fatty liver disease (MAFLD), formerly referred to as non-alcoholic fatty
liver disease (NAFLD), is a common liver disease characterized by an abnormal buildup of …

Autophagy mediates the degradation of intracellular macromolecules and organelles within
lysosomes. There are three types of autophagy: macroautophagy, microautophagy, and …

Excessive consumption of vegetable oils such as soybean and canolla oils containing ω-6
polyunsaturated fatty acids is considered one of the most important epidemiological factors …