Detection strategies of infectious diseases via peptide-based electrochemical biosensors

SB Hanoglu, D Harmanci, S Evran, S Timur - Bioelectrochemistry, 2024 - Elsevier
Infectious diseases have threatened human life for as long as humankind has existed. One
of the most crucial aspects of fighting against these infections is diagnosis to prevent …

Colorimetric sensing for translational applications: from colorants to mechanisms

Z Jin, W Yim, M Retout, E Housel, W Zhong… - Chemical Society …, 2024 - pubs.rsc.org
Colorimetric sensing offers instant reporting via visible signals. Versus labor-intensive and
instrument-dependent detection methods, colorimetric sensors present advantages …

A Protease-Responsive Polymer/Peptide Conjugate and Reversible Assembly of Silver Clusters for the Detection of Porphyromonas gingivalis Enzymatic Activity

M Retout, L Amer, W Yim, MN Creyer, B Lam… - ACS …, 2023 - ACS Publications
We report the reversible aggregation of silver nanoparticle (AgNP) assemblies using the
combination of a cationic arginine-based peptide and sulfur-capped polyethylene glycol …

An electrochemical biosensor based on electroactive peptide nanoprobes for the sensitive analysis of tumor cells

Y Zeng, X Qu, B Nie, Z Mu, C Li, G Li - Biosensors and Bioelectronics, 2022 - Elsevier
Peptides possess many appealing and desirable features, which have attracted increasing
attention in the field of electrochemical biosensing. However, peptides hardly produce …

EV71 virus induced silver nanoparticles self-assembly in polymer composites with an application as virus biosensor

W Sukjee, C Sangma, PA Lieberzeit… - Sensors and Actuators B …, 2023 - Elsevier
We conducted a set of experiments to show that EV71 virus could induce a self-assembly
process of silver nanoparticles in polyacrylamide. Silver nanoparticles were self-assembled …

Spacer matters: All-peptide-based ligand for promoting interfacial proteolysis and plasmonic coupling

Z Jin, C Ling, Y Li, J Zhou, K Li, W Yim, J Yeung… - Nano Letters, 2022 - ACS Publications
Plasmonic coupling via nanoparticle assembly is a popular signal-generation method in
bioanalytical sensors. Here, we customized an all-peptide-based ligand that carries an …

Peptide Amphiphile Mediated Co‐assembly for Nanoplasmonic Sensing

Z Jin, Y Li, K Li, J Zhou, J Yeung, C Ling… - Angewandte Chemie …, 2023 - Wiley Online Library
Aromatic interactions are commonly involved in the assembly of naturally occurring building
blocks, and these interactions can be replicated in an artificial setting to produce functional …

Goldilocks energy minimum: Peptide-based reversible aggregation and biosensing

W Yim, M Retout, AA Chen, C Ling… - … Applied Materials & …, 2023 - ACS Publications
Colorimetric biosensors based on gold nanoparticle (AuNP) aggregation are often
challenged by matrix interference in biofluids, poor specificity, and limited utility with clinical …

Di-arginine additives for dissociation of gold nanoparticle aggregates: a matrix-insensitive approach with applications in protease detection

M Retout, Z Jin, J Tsujimoto, Y Mantri… - … applied materials & …, 2022 - ACS Publications
We report the reversible aggregation of gold nanoparticles (AuNPs) assemblies via a di-
arginine peptide additive and thiolated PEGs (HS-PEGs). The AuNPs were first aggregated …

Empirical optimization of peptide sequence and nanoparticle colloidal stability: The impact of surface ligands and implications for colorimetric sensing

Z Jin, J Yeung, J Zhou, M Retout, W Yim… - … applied materials & …, 2023 - ACS Publications
Surface ligands play a critical role in controlling and defining the properties of colloidal
nanocrystals. These aspects have been exploited to design nanoparticle aggregation-based …