Mutating the CX3C motif in the G protein should make a live respiratory syncytial virus vaccine safer and more effective

S Boyoglu-Barnum, SO Todd, J Meng… - Journal of …, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) belongs to the family Paramyxoviridae and is the single
most important cause of serious lower respiratory tract infections in young children, yet no …

A first-in-human trial to evaluate the safety and immunogenicity of a G protein-based recombinant respiratory syncytial virus vaccine in healthy adults 18–45 years of …

X Cheng, G Zhao, A Dong, Z He, J Wang, B Jiang… - Vaccines, 2023 - mdpi.com
Background: With the enormous morbidity and mortality caused by respiratory syncytial virus
(RSV) infections among infants and the elderly, vaccines against RSV infections are in large …

A recombinant G protein plus cyclosporine A–based respiratory syncytial virus vaccine elicits humoral and regulatory T cell responses against infection without …

C Li, X Zhou, Y Zhong, C Li, A Dong, Z He… - The Journal of …, 2016 - journals.aai.org
Respiratory syncytial virus (RSV) infection can cause severe disease in the lower respiratory
tract of infants and older people. Vaccination with a formalin-inactivated RSV vaccine (FI …

Epidemiology of Respiratory Syncytial Virus Across Five Influenza Seasons Among Adults and Children One Year of Age and Older—Washington State, 2011/2012 …

ML Jackson, E Scott, J Kuypers, AK Nalla… - The Journal of …, 2021 - academic.oup.com
Background Vaccines and novel prophylactics against respiratory syncytial virus (RSV) are
in development. To provide a baseline for evaluating these interventions, we characterized …

[HTML][HTML] Evaluation of epidemiological and clinical features of influenza and other respiratory viruses

H Aktürk, M Sütçü, S Badur, SH Törün… - Turkish Archives of …, 2015 - ncbi.nlm.nih.gov
Aim: In our study, we aimed to clinically and epidemiologically evaluate respiratory tract
infections the viral agents of which were detected by molecular methods and to compare …

[HTML][HTML] One-year observational study of palivizumab prophylaxis on infants at risk for respiratory syncytial virus infection in Latin America☆

LM Castillo, G Bugarin, JC Arias, JIB Rangel… - Jornal de …, 2017 - SciELO Brasil
Objective: This study aims to describe real world palivizumab use and effectiveness in high-
risk Latin American infants and young children. Method: Prospective, multicenter …

Influenza virus: 16 years' experience of clinical epidemiologic patterns and associated infection factors in hospitalized children in Argentina

A Gentile, MF Lucion, M del Valle Juarez… - PLoS …, 2018 - journals.plos.org
Background Influenza is an important cause of acute lower respiratory tract infection (aLRTI),
hospitalization, and mortality in children. This study aimed to describe the clinical and …

Assessment and validation of syndromic case definitions for respiratory syncytial virus infections in young infants: a latent class analysis

K Lalani, I Yildirim, VK Phadke… - The Pediatric …, 2019 - journals.lww.com
Background: Respiratory syncytial virus (RSV) is a major cause of pediatric morbidity and
mortality worldwide. Standardized case definitions that are applicable to variety of …

[PDF][PDF] İnfluenza ve diğer solunum yolu virüslerinin klinik ve epidemiyolojik özelliklerinin değerlendirilmesi.

H Aktürk, M Sütçü, S Badur, S Hançerli Törün… - Türk Pediatri …, 2015 - turkarchpediatr.org
Öz Amaç: Çalışmamızda moleküler yöntemlerle viral etkeni saptanmış olan solunum yolu
enfeksiyonlarının klinik ve epidemiyolojik olarak değerlendirilmesi ve influenza ile diğer …

Reappraisal of respiratory syncytial virus as an aetiology of severe acute lower respiratory tract infections in children younger than 5 years in Nigeria

DM Oladele, DP Oladele, RM Ibraheem… - Transactions of The …, 2019 - academic.oup.com
Background Acute lower respiratory tract infections (ALRIs) especially severe ALRIs,
constitute a global high burden of morbidity and mortality in children< 5 y of age and …